Protein Alignment CG4757 and cest-24

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_504613.1
• Gene: cest-24 / 179017
• WormBaseID: WBGene00020891
• Length: 658
• Species: Caenorhabditis elegans
• Alignment Length: 542
• Identity: 147/542 - (27%)
• Similarity: 229/542 - (42%)
• Gaps: 94/542 - (17%)

  Fly    23 VDTELGRVRGANLTSRLGVNFHAFRGIRYAEPPLGDLRFVNPQPVKPWSPKIFDASEDGPMC--- 84
            |..:.|.:.|..:.:..|.....|.||.|||||:|:|||..|||.|.|        |....|
 Worm    98 VRVQQGLLEGFRVKTAKGDLCDVFHGIPYAEPPVGELRFQKPQPPKAW--------EGIRKCNKY 154

  Fly    85 -------PQPWDN---MTDVSEDCLRLNVYTKDLK--GRRPVIVFLHPGGFYVFSGQSKYLAGP- 136
                   ..|||.   ..:.|||||.|||:...::  .:.||:.::|.|| ||.....:|.|..
 Worm   155 PNRSIHKEMPWDKALPSANQSEDCLYLNVFAPKIREDKKYPVLFYIHGGG-YVMDSAERYTAKNI 218

  Fly   137 -EHFMDRDCVLVSLNYRLGSLGFLATGSKEAPGNAGLKDQVLALRWIQQHIQRFGGDPDSVTLLG 200
             :..:.|:.::|:.:||||.||||:||....|||.||.|.:.|:||:..:|..|||||:::||.|
 Worm   219 CKLLVSREIIVVTFHYRLGFLGFLSTGDDVCPGNYGLFDMLEAMRWVHANISSFGGDPENITLSG 283

  Fly   201 YSAGSISVALHMLSPMSRGLFHRGICMSAAPYGP-VKYKDNDL-QLAKRQAGLLKC-PQESIGEM 262
            .|||:.:..|...||:::|||.|.|.|....|.. ....::|: :..|:.|..|.. ||.:...
 Worm   284 QSAGAAAADLLSFSPLTKGLFKRKIVMGGNSYCHWATTSNHDIREYCKKWAKRLGWKPQLNYAN- 347

  Fly   263 VECMRRKPYLDYVSTYNG---------MF---------EFGWNPVLNWRIVVEKDFGQERYLIES 309
                :|:..:|..:.:||         ||         :....||::..|            :..
 Worm   348 ----KREESVDIFNFFNGLPTSKLGMTMFFSNTIFKECQLPLAPVIDGEI------------LPH 396

  Fly   310 PFKTARRGDFHKVALITGITEFEFLSGAFFDL--RNESIVNRYNRDWEHYASIALLLEQNSTQSR 372
            ..|..|....|..:|:.| .|:|.|......|  ..|..:|         ::|.:|..:|.. ||
 Worm   397 DLKVLRETQEHVPSLVGG-GEYEALLFCAIGLLRGTEKEIN---------SAIDVLSRKNRL-SR 450

  Fly   373 AASRVFREKYMPESLDKLEYPKSLKGM--GELLSDALIGVSFHRFLQ-LMSPHTPIYTYLFRYKG 434
            :......||...:| ..|......:.|  .:|:||.......:||:: ........|.|.|.::.
 Worm   451 SKIEAMTEKVYGDS-PALRADSKARKMFFVQLISDIFANYGNYRFMRDCQQRGVECYGYSFDHQS 514

  Fly   435 R--YTFLKNPDNQQTI---GPVHHDELIYLFHVGLLIPLLKREDPENFMIELLTRMWIEFAQKGD 494
            :  :.:|     |..:   |..|..||.|||....:...|.....:..:..:....:..|.:.|.
 Worm   515 KQMWGWL-----QHVVPFTGGTHTSELSYLFDCNYMSAPLGMNKTDKVVSGMTADYFTNFVKFGT 574

  Fly   495 PHNKNDEYLKGLNWPLYNAQDK 516
            |:..|.:..|   |...:..|:
 Worm   575 PNGPNSQLPK---WERISPDDE 593

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	147/542 (27%)
cest-24	NP_504613.1	COesterase	97..608	CDD:395084	147/542 (27%)