Protein Alignment CG4757 and cest-35.1

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_504400.1
• Gene: cest-35.1 / 178912
• WormBaseID: WBGene00015067
• Length: 545
• Species: Caenorhabditis elegans
• Alignment Length: 584
• Identity: 161/584 - (27%)
• Similarity: 245/584 - (41%)
• Gaps: 117/584 - (20%)

  Fly    17 SVLSIEVDTEL-----GRVRGANLTSRLGVNFHAFRGIRYAEPPLGDLRFVNPQPVKPWSPKIFD 76
            |.|..|.:||:     |.:|| |:..........:.||.:|:.|:|:|||......:.|:..: |
 Worm     6 SHLKPEHNTEVLNASCGPIRG-NIYEHDDKIVDGYLGIPFAKAPIGELRFKKSVEAEKWTEPL-D 68

  Fly    77 ASEDGPMCPQPW----------DNMTDVSED-CLRLNVYTKDLKGRR-----PVIVFLHPGGFYV 125
            ..:.||.|||..          ..:.:.:|| ||.|||:....|...     ||||:.:.|||.|
 Worm    69 CYKYGPGCPQSGALGAMIVPQASAIREFAEDNCLTLNVFAPKWKSAEFPNGLPVIVYFYGGGFEV 133

  Fly   126 -FSGQSKYLAGPEHFMD---------RDCVLVSLNYRLGSLGFLATGSKEAPGNAGLKDQVLALR 180
             ||..         |.|         :|.:||:.|||:|.|||.|||...:.||.||.||.|||:
 Worm   134 GFSSM---------FDDYSLTGTLPLKDVILVTPNYRIGPLGFFATGDDVSRGNWGLWDQALALQ 189

  Fly   181 WIQQHIQRFGGDPDSVTLLGYSAGSISVALHMLSPMSRGLFHRGICMSAA---PYGPVKYKDND- 241
            |:|:||:.|||||.:||:.|.|||..||....|||.:...||:.|.||.|   |:| ::.||.:
 Worm   190 WVQKHIKSFGGDPSNVTISGTSAGGASVDFLSLSPHANKYFHKFIPMSGAATCPFG-IRSKDVEG 253

  Fly   242 ---LQLAKRQAGLLKCPQESIGEMVECMRRKPYL---DYVSTYNGMFEFGWNPVLNWRIVVEKDF 300
               .:.||.. |......||:....:....:.:|   .:....:|||.|    |.|:    :.||
 Worm   254 LIFREFAKHH-GYAGNDSESLLHWYQSQDAEIFLKAEGFKYPASGMFSF----VPNY----DGDF 309

  Fly   301 GQERYLIESPFKTARRGDFHKVALITGITEFEFLSGAFFDLRNESIVNRYNRDWEHYASIALLLE 365
                  ...||...|: :..|:..|..:.|:|   |..|:              |.|..
 Worm   310 ------FPKPFDELRK-EAPKLDAIVSVAEYE---GLGFE--------------EFYPG------ 344

  Fly   366 QNSTQS-----------RAASRVFR---EKYMPESLDKLEYPKSLKGMGELLSDALIGVS-FHRF 415
            |.|.|.           |....|.:   |.|: |:::.....|..|.:.|:..|....|. |...
 Worm   345 QKSPQEVLTAALGPEVVRNREEVVKKAVEAYL-ENIEDKSGEKIGKKLVEIFGDYYFSVGVFDTV 408

  Fly   416 LQLMSPHTPIYTYLFRYKGRYTFLKNPDNQQTIGPVHHDELIYLFHVGLLIPLLKREDPENFMIE 480
            ..|......:|...|.|....|.:...:|:......|..::.|:...|  |....:||.:  :::
 Worm   409 RSLAKYGNNVYLSSFNYFNPETPIMFGENRPFNAASHGCDIRYILGDG--IGEFSKEDRK--VMD 469

  Fly   481 LLTRMWIEFAQKGDPHNKNDEYLKGLNWPLYNAQDKG-YLEIGNNLTAKSGGFFLNRYQIWEDL 543
            ::......||:.|:|:.|.    ..:.|..|:..:.| |.:|.......:..|...||:|.:::
 Worm   470 MMGTYLTNFAKYGNPNGKG----VSIPWEKYSLDNPGRYFKIDYPKCEMADNFLDGRYKIIDEV 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	158/576 (27%)
cest-35.1	NP_504400.1	COesterase	16..523	CDD:395084	153/566 (27%)