Protein Alignment CG4757 and cest-32

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_504397.1
• Gene: cest-32 / 178909
• WormBaseID: WBGene00016862
• Length: 545
• Species: Caenorhabditis elegans
• Alignment Length: 538
• Identity: 137/538 - (25%)
• Similarity: 240/538 - (44%)
• Gaps: 83/538 - (15%)

  Fly    44 HAFRGIRYAEPPLGDLRFVNPQPVKPWSPKIFDASEDGPMCPQPWDNMTDV---------SEDCL 99
            :.:.||.:|:.|:.:|||..|...:.|: |..:..:.||.|||....::::         .::||
 Worm    37 NGYLGIPFAKAPICELRFKKPVEAEKWT-KPLNCHKYGPGCPQSGHMISNLLPPGYREFAEDNCL 100

  Fly   100 RLNVYTKDLKGRR-----PVIVFLHPGGFYV-FSGQSKYLAGPEHFMD---------RDCVLVSL 149
            .||::....|...     |::|:.|.|||.: ||..         |.|         :|.::|:.
 Worm   101 NLNIFAPSWKSEEFPNGLPIMVYFHGGGFEIGFSSM---------FDDYSLSGTLPLKDVIVVTA 156

  Fly   150 NYRLGSLGFLATGSKEAPGNAGLKDQVLALRWIQQHIQRFGGDPDSVTLLGYSAGSISVALHMLS 214
            |||:|.|||:.||.:.:.||.||.||.|||:|:|:||:.|||:|:.||:.|.|||.:|..|..||
 Worm   157 NYRVGPLGFMTTGDEVSRGNYGLWDQTLALKWVQEHIKSFGGNPNIVTVCGTSAGGVSAGLLALS 221

  Fly   215 PMSRGLFHRGICMSAAPY--GPVKYKDNDLQLAKRQAGLLKCPQESIGEMVECMRRKPYLDYVST 277
            |.|..||||.:.||.:.:  ..::.|:.:.::.:..|.......|....::|..:.:|...:..|
 Worm   222 PHSNKLFHRFMAMSGSAFCEFSIRTKEQEAEIFRNFAKHHGYEGEDSESLLEWYKSQPLSKFQET 286

  Fly   278 YNGMFEFGWNPVLNWRIVVEKDFGQERYLIESPFKTARRGDFHKVALITGITEFE---FLSGAFF 339
              ..||...:..|.:....:.||      ...||....| :..|:..:..:.|:|   ||: .|.
 Worm   287 --ATFEKKASGFLTFIPNFDGDF------FPKPFDELSR-EAPKLDAMATVDEYEGLGFLT-MFQ 341

  Fly   340 DLRNES--IVNRYNRDWEHYASIALLLEQNSTQSRAASRVFREKYMPESLDKLEYPKSLKGMGEL 402
            ..||:.  |.:.:..|          :.:|:..   ..:...|.|| :::||.:.....|.:.:|
 Worm   342 SRRNDMDIIKSSFGSD----------VVENAVD---VQKRIMEFYM-KNIDKNDDKAVEKRLIQL 392

  Fly   403 LSDALIGVSFHRFLQLMSPHTPIYTYLFRYKGRYTFLKNPDNQQTIGPV----HHDELIYLFHVG 463
            :||:...:.   .|:.:...|...:..:.....|..:.:.|...|..|.    |..||.|:...|
 Worm   393 ISDSWFNIG---ALETVKTSTKYGSNAYLGSFDYYNMGSNDPYATWFPFKAANHGSELKYMLGEG 454

  Fly   464 L--LIPLLKREDPENFMIELLTRMWIEFAQKGDPHNKNDEYLKGLNWPLYNAQDK-GYLEIGNNL 525
            :  ..|:    :.|..:|:::..:...|.:.|:|:..|...|    |..|..:.. .|.:|....
 Worm   455 MGKFSPI----EEEFKVIDMMGTLTANFVKYGNPNGINGPEL----WKKYTPEKPYSYFKIDYPK 511

  Fly   526 TAKSGGFFLNRYQIWEDL 543
            :.....|...|.:::||:
 Worm   512 SEMRDNFQDGRLKLFEDI 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	135/533 (25%)
cest-32	NP_504397.1	COesterase	16..519	CDD:395084	133/526 (25%)