Protein Alignment CG4757 and cest-10

DIOPT Version :9

• Sequence 1: NP_001262469.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_501133.3
• Gene: cest-10 / 177493
• WormBaseID: WBGene00016595
• Length: 579
• Species: Caenorhabditis elegans
• Alignment Length: 581
• Identity: 144/581 - (24%)
• Similarity: 253/581 - (43%)
• Gaps: 135/581 - (23%)

  Fly     1 MLMLFVVELLVLLA-SSSVLSIEVDTELGRVRGANLTSRLGVNFHAFRGIRYAEPPLGDLRFVNP 64
            |.:|..:::|.|.: |..|.|:.|:|.||::.|    .::| |||.|:.|.:|:||||.|||..|
 Worm     1 MHLLPGIQILFLFSFSCFVDSVIVETSLGKLNG----DQIG-NFHLFKKIPFAKPPLGKLRFQKP 60

  Fly    65 QPVKPWSPKIFDASEDGPMC---------PQPWDNMTDVSEDCLRLNVYTKD--LKGRR-PVIVF 117
            ||.:.|: .:.:|.:.||.|         .|.|     |.||||.||::|.:  ||.:. .|:::
 Worm    61 QPAETWN-GVRNAKDYGPACMSNSSTTKTVQKW-----VDEDCLHLNIFTSETCLKSKNCAVVIY 119

  Fly   118 LHPGGFYVFSG---QSKYLAGPEHFMDRDCVLVSLNYRLGSLG-FLATGSKEAPGNAGLKDQVLA 178
            ||.|..:..|.   ...:|.  ..:..::.|.|....|||... |:......||.|..|.|.:.|
 Worm   120 LHGGNLHYDSAVMFNDTFLL--HTYASQEIVFVIPAVRLGIFSHFVVEDQSIAPNNLALFDMLQA 182

  Fly   179 LRWIQQHIQRFGGDPDSVTLLGYSAGSISVALHMLSPMSR-----GLFHRGICMSAAPYGPVKYK 238
            :.:.:..|..|||:....||||:|.|. :|| .|||..::     .||.:.|.||:    |..:.
 Worm   183 MEFAKSDIHNFGGNNKRTTLLGHSYGG-TVA-SMLSFSTKVNTDLSLFQQYISMSS----PTNFD 241

  Fly   239 DNDLQLAK------------RQAGLLKCPQESIGEMVECMRRKPYLDYVSTYNGMFEFGWNPVLN 291
            ..:||:.:            :.:..::..|:.: .|.:|:::|...:.:.....:.|.|: ||..
 Worm   242 TLELQVERTYRFAEHANCLPKNSKFMRKNQKEV-YMRDCLKKKSASELLRIQRSLEEAGY-PVYG 304

  Fly   292 WRI--------VVEKDFGQERYLIESPFKTARRGDFHKVALITGITEFEFLSGAFFDLRNESIVN 348
            ..:        |:|:||      ::||         :.:..:||.|::            ||:|
 Worm   305 GSVMRGPIFQEVLERDF------MDSP---------NNITSLTGCTKY------------ESLV- 341

  Fly   349 RYNRDWEHYASIALLLEQNSTQSRAASRVFREKYMPESLD-KLEYPKSLKGMGELLSDALIGVSF 412
                 ::||.::...|...:.:.      ..|||..:|.: |:|: .::|...:::   ||.:.
 Worm   342 -----YDHYRNMGKALGFENYEE------VNEKYRSDSKEGKIEF-DNVKNATQIM---LIQIR- 390

  Fly   413 HRFLQLMSPHTPIYTYLFRYKGRYTFLKNPDNQQTIGPVHHDELIYLFHVGLLIPLLKREDPENF 477
            .|..:::..:.|.|.|      .|.:.|:.:        |.|:|.::..|.   |.::.|: |..
 Worm   391 TRVNKILKKNIPAYHY------EYAYPKHAN--------HTDDLFFIMGVH---PFIQDEN-EIK 437

  Fly   478 MIELLTRMWIEFAQKGDPHNKNDEYLKGLNWPLYNAQDKGYLEIGNNLTAKSGGFFLNRYQ 538
            :......|::.|.:.|:|.|..|.         .|.....|.|:..|.|........|.::
 Worm   438 LGNFYRSMFLNFIKTGNPGNGCDG---------ANLNGSTYFEVNWNETTGERPVMKNNFE 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_001262469.1	COesterase	15..540	CDD:278561	140/566 (25%)
		Aes	40..>204	CDD:223730	61/179 (34%)
cest-10	NP_501133.3	Abhydrolase	23..503	CDD:389770	137/559 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156918
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.740