Protein Alignment CG4757 and cest-25

DIOPT Version :9

• Sequence 1: NP_001262469.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_497609.1
• Gene: cest-25 / 175390
• WormBaseID: WBGene00022178
• Length: 550
• Species: Caenorhabditis elegans
• Alignment Length: 529
• Identity: 154/529 - (29%)
• Similarity: 239/529 - (45%)
• Gaps: 94/529 - (17%)

  Fly    20 SIEVDTELGRVRGANLTSRLGVNFHAFRGIRYAEPPLGDLRFVNPQPVKPWS----PKIFDA--- 77
            |.:|.|..|.:.|..|.........||:||.||.||:|:|||..|||.:.|:    .|.|.|
 Worm    16 SRQVLTSYGPIEGRRLIHEGEKQVDAFQGIPYAAPPIGNLRFALPQPHEKWTEVRETKSFGARGI 80

  Fly    78 SEDGPMCPQPWDNMTDVSEDCLRLNVYT-----KDLKGRRPVIVFLHPGGFYVFSGQSKY--LAG 135
            .:|..:.|:    .:..|||.|.||::|     |:..| .|||:::|.||| |.....||  ::.
 Worm    81 QKDHVLSPK----TSPQSEDNLTLNIFTPVWTPKNETG-FPVILYIHGGGF-VSDSAHKYGDMSI 139

  Fly   136 PEHFMDRDCVLVSLNYRLGSLGFLATGSKEAPGNAGLKDQVLALRWIQQHIQRFGGDPDSVTLLG 200
            .:|.:.:|.|:|::.||||.|||..||....|.|..|.|.|.||:|::::|..|.|||:::||:|
 Worm   140 CQHLVTKDVVVVTIQYRLGFLGFWTTGDSSIPDNVALHDMVFALKWVKENIGLFNGDPNNITLMG 204

  Fly   201 YSAGSISVALHMLSPMSRGLFHRGICMSAAPYGPVKYKDNDLQLAKRQAGLLKCPQESIG----- 260
            .|||..||....:||:||.||.:.|.|..............|...:.:|       :.||
 Worm   205 QSAGGASVDFLSISPVSRDLFQKVIPMGGNASCSWAIHPRPLNACRNRA-------QEIGVFDGM 262

  Fly   261 ---EMVECMRRKPYLDYVSTYNGMFEFGWNPVLNWRIVVEKDFGQ-------ERYLIESPFKTAR 315
               :.||.:|..|...:.|            .||...|..|...:       :...|..|....|
 Worm   263 NTLDWVEKLRELPADKFAS------------ALNMEAVDTKTDPELLIGPKYDNLFIPRPVMELR 315

  Fly   316 RGDFHKVALITGITEFEFLSGAFFDLRNESIVNRYNRDWEHYASIALLLEQNSTQSRAASRVFRE 380
            :....|..|: |..:.|.|..|||.|..:..::...:|      ::.:|.:.....:|  |.::|
 Worm   316 KEAPMKPRLL-GCAKSEGLVFAFFGLNTKHPLHAVQQD------VSAILSEKLFPLKA--RDYQE 371

  Fly   381 KYMPESLDKL-----EYPKS--LKGMGELLSDALIGVSFHR-FLQLM--SPHTPIYTYLFRYKGR 435
            |    :|:||     ::.|.  .:.|.:|..|:.:.|...: .|.::  .|.||||.|.|.|
 Worm   372 K----ALEKLIEIGTDHSKEEWQRAMVDLKGDSFLNVGIQQNVLDVLETQPSTPIYMYSFDY--- 429

  Fly   436 YTFLKNPDNQQTIG-------PVHHDELIYLFHVG-LLIPLLKREDPENFMIELLTRMWIEFAQK 492
                .||.....:|       ..|..::.|:  || .::......:.:..|||:.||:|..||:.
 Worm   430 ----CNPKAYGIMGFKLPFKDATHCTDISYV--VGNHIVNSFDFNEEDYKMIEITTRLWTNFAKY 488

  Fly   493 GDPHNKNDE 501
            |:|:.:.|:
 Worm   489 GNPNGEGDD 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_001262469.1	COesterase	15..540	CDD:278561	154/529 (29%)
		Aes	40..>204	CDD:223730	70/177 (40%)
cest-25	NP_497609.1	COesterase	18..536	CDD:365897	153/527 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810