Protein Alignment CG4757 and ace-3

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_496963.1
• Gene: ace-3 / 175076
• WormBaseID: WBGene00000037
• Length: 607
• Species: Caenorhabditis elegans
• Alignment Length: 628
• Identity: 168/628 - (26%)
• Similarity: 262/628 - (41%)
• Gaps: 121/628 - (19%)

  Fly     9 LLVLLASSSVLS-------------IEVDTELGRVRGANLTSRLGVNFHAFRGIRYAEPPLGDLR 60
            ||:||::::.|.             :||.|:||.|||.. :........:|.|:.:||||:.:.|
 Worm     7 LLLLLSTTTFLRVSTAQQDEPKASVVEVQTKLGTVRGTE-SDHGNKRVRSFLGVPFAEPPINEHR 70

  Fly    61 FVNPQPVKPWSPKIFDASEDGPMC-------------PQPWDNMTDVSEDCLRLNVYTKDLKGRR 112
            |..|.|.:||:..| .|:...|.|             .:.|:..|.||||||.:|::........
 Worm    71 FKKPTPARPWNGTI-SANTLSPACFQGRDSYDPTFWGSEMWNANTPVSEDCLYVNIWAPADAYNL 134

  Fly   113 PVIVFLHPGGFYVFSGQSKYLAGPEHFMDRDCVLVSLNYRLGSLGFLATGSKEAPGNAGLKDQVL 177
            .|:|:|..|||:..|.......|.|.....:.::|::|||:|..|:|....::.|||.|:.||.|
 Worm   135 TVLVWLFGGGFWYGSPSLLLYDGKELATRGNVIVVNINYRVGPFGYLFLDHEDVPGNMGMLDQQL 199

  Fly   178 ALRWIQQHIQRFGGDPDSVTLLGYSAGSISVALHMLSPMSRGLFHRGICMSAAPYGPVKYKDNDL 242
            ||.||:.||..|||:|..::|:|.|||:.|:..|:::|.|:|||..||..|.:...  |:..:..
 Worm   200 ALYWIRDHIFSFGGNPARISLVGESAGAASIVAHLIAPASKGLFQNGILQSGSLDN--KWSMDSP 262

  Fly   243 QLAKRQ----AGLLKCPQESIGEMVECMRRKP---YLDYVSTYNGMFEFGWNPVLNWR----IVV 296
            :.||::    |.|:.|.|..|.:...|:|..|   .:|.:          ||..||:.    .:|
 Worm   263 KRAKQKSTALADLVGCNQTKITDQTACLRNTPAQLLIDNI----------WNVGLNFLEFPFAIV 317

  Fly   297 EKDFGQERYLIESPFKTARRGDFH-KVALITGITEFEFLSGAFFDLRN-------ESIVNRYNRD 353
            .||....::|  ..|...|.|.:. .|.|:.||...|   |.|:::.|       :|:....:||
 Worm   318 SKDQNFFKHL--DGFIALREGTYSTDVNLMFGINHDE---GNFWNIYNLAKFFDKQSVKPGLDRD 377

  Fly   354 WEHYASIALLLEQNSTQSRAASRVFREKYMPESLDKLEYPKSLKGMGELLSDALIGVSF------ 412
            ..|.........|......||..|:.:   |:..|    ||..........:.::|..|
 Worm   378 EFHECVDTAFAVQPELVRTAAKYVYSD---PKCTD----PKKKTDFYTEQVNQMVGDYFFTCDSI 435

  Fly   413 ---HRFLQLMSPHTPIYTYLFRYKGRYTFLKNPDNQQTIGPVHHDELIYLFHVGLLIPLLKREDP 474
               |.:.::....:.::.|.|.....    .||..:.| |.:|..|:.|:|.|.|..........
 Worm   436 WFAHNYPKMAGNQSNVFVYYFDQPSS----ANPWPKWT-GVMHGYEIEYVFGVPLHNTTAGYTKE 495

  Fly   475 ENFMIELLTRMWIEFAQKGDPHNKN-----------DEY---------------------LKGLN 507
            |..:.|.:...|..||..|.|..:.           |.|                     :|.:.
 Worm   496 EMDVSEKVIDFWTTFANTGVPSLRKRAVGTTQKIKWDRYDGTDHTTWMNIKTGSFRMIQEIKKVE 560

  Fly   508 WPLY-NAQDKGYLEIGNNLTAKSGGFFLNRYQIWEDLFPLSSF 549
            ..|: ||:|..|......|...|.. .|.:|.|:  |..||:|
 Worm   561 CDLWRNAKDMEYSAYKEELATTSSS-TLTQYTIY--LILLSAF 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	158/606 (26%)
ace-3	NP_496963.1	COesterase	33..564	CDD:395084	149/561 (27%)