Protein Alignment CG4757 and ace-2

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_491141.1
• Gene: ace-2 / 171905
• WormBaseID: WBGene00000036
• Length: 629
• Species: Caenorhabditis elegans
• Alignment Length: 593
• Identity: 159/593 - (26%)
• Similarity: 245/593 - (41%)
• Gaps: 143/593 - (24%)

  Fly    23 VDTELGRVRGANLTSRLGVNFHAFRGIRYAEPPLGDLRFVNPQPVKPWSPKIFDASEDGPMC--- 84
            |.|.||.:||...|.. |....||.|:.||:||:|..||...:.:..||.:: :|......|
 Worm    41 VHTPLGTIRGVGQTFD-GAKVSAFLGVPYAKPPIGSRRFKMAEMIDRWSGEL-EARTLAKTCYLT 103

  Fly    85 -----PQ-----PWDNMTDVSEDCLRLNVYT-KDLKGRRPVIVFLHPGGFY-------VFSGQSK 131
                 ||     .|:....:|||||.:|::. :|..|  .|:|:::.|||:       ::||  .
 Worm   104 IDSAFPQFPGAEMWNPPGAISEDCLNMNIWVPEDHDG--SVMVWIYGGGFFSGTPSLDLYSG--S 164

  Fly   132 YLAGPEHFMDRDCVLVSLNYRLGSLGFLATGSKEAP--GNAGLKDQVLALRWIQQHIQRFGGDPD 194
            ..|..||     .::|::|||||..|||..|. ::|  ||.||.||.|||||:.::|..||||..
 Worm   165 VFAAKEH-----TIVVNVNYRLGPFGFLYFGD-DSPIQGNMGLMDQQLALRWVHENIGAFGGDRS 223

  Fly   195 SVTLLGYSAGSISVALHMLSPMSRGLFHRGICMSA------APYGPVKYKDNDLQLAKRQAGLLK 253
            .|||.|.||||.|...|:.:|.|...|...|..|.      |...|....|...:|||:    :.
 Worm   224 RVTLFGESAGSASTTAHLFAPNSHKYFRNIIAKSGSIINSWASATPPTMLDLSFRLAKK----VN 284

  Fly   254 CPQESIGEMVECMRRKP------YLDYVSTYNG-MFEFGWNPVLN---------WRIVVEKDFGQ 302
            |....:..:|:|:|..|      ..|.:|...| ...|.:.||.:         ::.:..|.|.:
 Worm   285 CSSPDMNAIVKCLRSVPAHLVQAEADNISGDIGPPMTFAYVPVSSDANFFQGDVFQKLANKQFKK 349

  Fly   303 ERYLIESPFK----------------------TARRGDFHKVALITGITEFEFLSGAF--FDLRN 343
            :..:|....|                      |....|.|..||||. ..:|....||  :...:
 Worm   350 DVNIIFGSVKDEGTYWLPYYMSLPKYGFAFNHTISAEDPHNRALITR-DHYEESMRAFMPYFAGS 413

  Fly   344 ESIVNRYNRDWEHYASIALLLEQNSTQSRAASRVFREKY---MPESLDKLEYPKSLKGMGELLSD 405
            :.::|.:...:||.::               |.|..|:|   :...|..|.:..||....:|:||
 Worm   414 KLVLNAFMNSYEHVST---------------SNVPEERYRDGVARFLGDLFFTCSLIDFADLISD 463

  Fly   406 ALIGVSFHRFLQLMSPHTPIYTYLFRYKGRYTFLKNPDNQQTIGPVHHDELIYLFHVGLLIPLLK 470
            .:.|              .:|.|.|.|:..    .|| ..:.:|.:|..|:.|.|......|.|.
 Worm   464 NIFG--------------NVYMYYFTYRSS----ANP-WPKWMGVMHGYEIEYAFGQPYWRPHLY 509

  Fly   471 RE---DPENFMIELLTRMWIEFAQKGDPHNKNDEYLKGLNWPLYNAQDKGYLEIGNN-------- 524
            .:   :.|..:..::.::|..||..|    :.|.:     ||.||..::..:|:|..
 Worm   510 DQTHLEDEKRLSSIIMQIWANFANTG----RTDSF-----WPQYNKIERKAIELGETTLQGKHRI 565

  Fly   525 LTAKSGGF 532
            ::...|||
 Worm   566 ISDVHGGF 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	159/593 (27%)
ace-2	NP_491141.1	COesterase	40..558	CDD:395084	156/576 (27%)