Protein Alignment CG4757 and cest-27

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_871861.2
• Gene: cest-27 / 171610
• WormBaseID: WBGene00018958
• Length: 561
• Species: Caenorhabditis elegans
• Alignment Length: 535
• Identity: 152/535 - (28%)
• Similarity: 233/535 - (43%)
• Gaps: 109/535 - (20%)

  Fly    24 DTELGRVRGANLTSRLGVNFHAFRGIRYAEPPLGDLRFVNPQPVKPWSPKIFDASEDGPMCPQ-- 86
            |...|.::|.......|.....|.||.|||||:|.|||..|...:.|:..: |....||..||
 Worm    29 DATCGPIKGVGYEQEDGSVVEGFLGIPYAEPPIGALRFKKPVAHRKWTEPL-DCVRFGPRSPQND 92

  Fly    87 ----PWDNMTDVSED-CLRLNVYTKDLKGRR-----PVIVFLHPGGFYVFSGQSKYLAG-PEHFM 140
                .:.|....||: ||.|||:|...:...     ||:||:|.|||.|.|..:...|. ..:..
 Worm    93 ELLGQFVNTVGKSEEHCLSLNVFTPKWESNEWPDGFPVMVFIHGGGFAVHSSSNYGCASIARNLC 157

  Fly   141 DRDCVLVSLNYRLGSLGFLATGSKEAPGNAGLKDQVLALRWIQQHIQRFGGDPDSVTLLGYSAGS 205
            .:|.|:|::|||||.|||..||.:...||.||.||..||.|:|::||.|.||||:||:.|.|||.
 Worm   158 TKDVVVVTINYRLGVLGFFTTGDEVCRGNLGLWDQTAALEWVQENIQSFRGDPDNVTIFGQSAGG 222

  Fly   206 ISVALHMLSPMSRGLFHRGICMSAAPYGPVKYKDNDLQLAKRQAGLLKCPQESIG---------E 261
            .||.|..|||.|||||:|.|.|  |..|..   |..::.:::||.|.:.....:|         :
 Worm   223 ASVDLLCLSPHSRGLFNRAIPM--AGNGEC---DFAMRTSEQQAQLSREFARYLGWEGDDNDSED 282

  Fly   262 MVECMRRKPYLDYVSTYNGMFEFGWNP--------------VLNWRIVVEKDFGQERYLIESPFK 312
            :::      ::|....|.  .|.|.||              |.|:    :.||      ...|..
 Worm   283 LLQ------FIDQQPLYK--IEMGINPKRGFKHSQAGSLYFVPNF----DGDF------FPKPLN 329

  Fly   313 TARRGDFHKVALITGITEFEFLSGAFFDLRNESIVNRYNRDWEHYASIALLLEQNSTQSRAASRV 377
            ..|: :..|:.::||.|::|   |.||                  .::..|.:......:...|:
 Worm   330 QLRK-EAPKMQIMTGTTKYE---GLFF------------------IALGALSKNPEGIKKFMGRI 372

  Fly   378 FREKYMPESLDKL---------------EYPKSLKGMGELLSDALIGVSFHRFLQLMSP-HTPIY 426
            |:|....|..|.:               ::.|::..:.:.:.|..|....:|...:|:. ...:|
 Worm   373 FKECDYGERADDVLQMVYDFYFKGVHPKDHEKNMHQIVKFIGDYSINYGTYRLANIMTDLQHDVY 437

  Fly   427 TYLFRYK-----GRYTFLKNPDNQQTIGPVHHDELIYLFHVGLLIPLLKREDPENFMIELLTRMW 486
            .|.|.|.     |.:.:|     ...:|..|..|:.|:...| :|...:..|.:..|:.::|..:
 Worm   438 FYQFDYHNSAGFGVFRWL-----LPFLGSTHCTEMRYVLGKG-IISKFRPNDNDKKMLHVMTTYF 496

  Fly   487 IEFAQKGDPHNKNDE 501
            ..||:.|:|:.:|.|
 Worm   497 TNFAKYGNPNGENQE 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	152/535 (28%)
cest-27	NP_871861.2	COesterase	29..548	CDD:395084	152/535 (28%)