Protein Alignment CG4757 and Nlgn3

DIOPT Version :9

• Sequence 1: NP_001262469.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_599163.2
• Gene: Nlgn3 / 171297
• RGDID: 621119
• Length: 848
• Species: Rattus norvegicus
• Alignment Length: 672
• Identity: 177/672 - (26%)
• Similarity: 270/672 - (40%)
• Gaps: 198/672 - (29%)

  Fly    10 LVLLASSSVLSIEVDTELGRVRGAN--LTSRLGVNFHAFRGIRYAEPPLGDLRFVNPQPVKPWSP 72
            |||.||:...:..|:|..|::|||.  |.|.:......:.|:.||.||:|:.||:.|:|...||
  Rat    31 LVLRASTQAPAPTVNTHFGKLRGARVPLPSEILGPVDQYLGVPYAAPPIGEKRFLPPEPPPSWS- 94

  Fly    73 KIFDASEDGPMCPQ------------PW---------DNMTDVSEDCLRLNVY--TKDLK----- 109
            .|.:|:...|:|||            .|         ..:.:.:||||.||||  |:|:|
  Rat    95 GIRNATHFPPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYLNVYVPTEDVKRISKE 159

  Fly   110 --------------------------------------GRRPVIVFLHPGGFYVFSGQSKYLAGP 136
                                                  |.:||:|::| ||.|: .|....:.|.
  Rat   160 CARKPNKKICRKGGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVYIH-GGSYM-EGTGNMIDGS 222

  Fly   137 EHFMDRDCVLVSLNYRLGSLGFLATGSKEAPGNAGLKDQVLALRWIQQHIQRFGGDPDSVTLLGY 201
            ......:.::::||||:|.||||:||.:.|.||.||.||:.||||:.::|..|||||..:|:.|.
  Rat   223 VLASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGS 287

  Fly   202 SAGSISVALHMLSPMSRGLFHRGICMS-------AAPYGPVKYKDNDLQLAKRQAGLLKCPQESI 259
            ..|:..|:|..||..|.|||.|.|..|       |..|.||||    ..|...:.|   |.....
  Rat   288 GIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKY----TSLLADKVG---CNVLDT 345

  Fly   260 GEMVECMRRKPYLDYVSTYNGMFEFGWNPVLNWRIVVEKDFGQERYLI------------ESPFK 312
            .:||:|:|:|                     :.:.:||:|....||.:            :.|..
  Rat   346 VDMVDCLRQK---------------------SAKELVEQDIQPARYHVAFGPVIDGDVIPDDPEI 389

  Fly   313 TARRGDFHKVALITGITEFEFL-------------SGAFFDLRNESIV-NRYNRDWEHYASIALL 363
            ...:|:|....::.|:.:.|.|             ||..||....:.| |.|...
  Rat   390 LMEQGEFLNYDIMLGVNQGEGLKFVEGVVDPEDGVSGTDFDYSVSNFVDNLYGYP---------- 444

  Fly   364 LEQNSTQSRAASRVFRE--KYMPESLDKLEYPKS-LKGMGELLSD------ALIGVSFH-RFLQL 418
             |...|        .||  |:|.......:.|:: .|.:..|.:|      :::....| |:
  Rat   445 -EGKDT--------LRETIKFMYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARY--- 497

  Fly   419 MSPHTPIYTYLFRYKGRYTFLKNPDNQQTIGPVHHDELIYLFHVGLLIPLLKRED--PENF---- 477
               .:|.|.|.| |....:.:|...:.    ..|.||:.|:|.|    |::...|  |.||
  Rat   498 ---GSPTYFYAF-YHHCQSLMKPAWSD----AAHGDEVPYVFGV----PMVGPTDLFPCNFSKND 550

  Fly   478 --MIELLTRMWIEFAQKGDP-----------HNKNDEYLKGLNWPLYNAQDKGYLEIGNNLTAKS 529
              :..::...|..||:.|||           |.|.:.: :.:.|..||.:|:.||.||.....:.
  Rat   551 VMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKANRF-EEVAWSKYNPRDQLYLHIGLKPRVRD 614

  Fly   530 GGFFLNRYQIWEDLFP-LSSFH 550
             .:...:...|:.|.| |.:.|
  Rat   615 -HYRATKVAFWKHLVPHLYNLH 635

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_001262469.1	COesterase	15..540	CDD:278561	168/654 (26%)
		Aes	40..>204	CDD:223730	70/229 (31%)
Nlgn3	NP_599163.2	COesterase	40..624	CDD:395084	167/650 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	169..195		0/25 (0%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	645..691

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336085
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740