Protein Alignment CG4757 and LOC1281452

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: XP_321363.5
• Gene: LOC1281452 / 1281452
• VectorBaseID: AGAMI1_014190
• Length: 562
• Species: Anopheles gambiae
• Alignment Length: 587
• Identity: 176/587 - (29%)
• Similarity: 272/587 - (46%)
• Gaps: 83/587 - (14%)

  Fly     1 MLMLFVVELLVLLA--SSSVLSIEVDTELGRVRGANLTSRLGVNFHAFRGIRYAEPPLGDLRFVN 63
            ||...||..||.||  :.......::|..|:::|...:..|..::.||.||.||:||:|:|||.|
Mosquito     1 MLKFVVVLSLVALAVHAQDASRPIINTSGGQIQGITASCGLFCSYFAFNGIPYAQPPVGELRFRN 65

  Fly    64 PQPVKPWSPKIFDASEDGPMCPQ-PWDNMTDVSEDCLRLNVYTKDLKGRRPVIVFLHPGGFYVFS 127
            |:|...|. .:.|.||....||. .:......|||||.|||||::|.|.|||:|::|.|.|...|
Mosquito    66 PRPHGGWQ-GVKDGSEHRSTCPSGGFLGGVSGSEDCLYLNVYTQNLIGSRPVMVWIHGGSFTGGS 129

  Fly   128 GQSKYLAGPEHFMDRDCVLVSLNYRLGSLGFLATGSKEAPGNAGLKDQVLALRWIQQHIQRFGGD 192
            |.| ::.||::.|..|.|:|::|||||.|||.:|....|.||.|:||.|:||:|::|:|..||||
Mosquito   130 GNS-WIYGPDNLMPEDVVVVTINYRLGILGFFSTDDVHAAGNWGMKDCVMALQWVRQNIAAFGGD 193

  Fly   193 PDSVTLLGYSAGSISVALHMLSPMSRGLFHRGICMSAAPYGPVKYKDNDLQLAKRQAGLLKCPQE 257
            |::||:.|.|||.::|...:||..:.||||:.|..|.....|..::....:||.|.|.......:
Mosquito   194 PNNVTIFGESAGGVAVHYLVLSNKASGLFHKAIAQSGTALVPWGFQYRPRELAYRLADRFGYSHD 258

  Fly   258 SIGEMVECMRRKPYLDYVSTYNGMFEF----GWNPVLNWRIVVEKDF---------GQERYLIES 309
            | ..:|:.:|..|....:.|..|..:.    |:.|.         ||         .:|.:|.:.
Mosquito   259 S-ATLVQSLRNTPIETLIETQEGWLDIEIPRGFKPF---------DFVPNAEPVNSPEETFLTQL 313

  Fly   310 PFKTARRGDFHKVALITGITEFEFLSGAFFDLRNESIVNRYNRDWEHYASIALLLEQNSTQSRAA 374
            |......|.|:.|..|.|....|.|...:....:.::.|.:.|:.:::......:...:..|.|.
Mosquito   314 PIDIINAGTFNHVPFIAGYMSMESLFMVYEHTIDSTVWNAFTRNPDYFVPHFWNIPHGTAASAAV 378

  Fly   375 SRVFREKYMPESLDKLEYPKSLKGMGELLSDALI-GVSFH---RF---------LQLMSPHTPIY 426
            |:..|..|..:           :.:|   :|.:: .::||   :|         |.......|.|
Mosquito   379 SQGIRNAYWQD-----------RPLG---NDIMVEWLTFHTDQQFIYAIDKTVRLHAQRSSAPTY 429

  Fly   427 TYLFRYKGRYTFLKN-------PDNQQTIGPVHHDELIYLFHVG--LLIPLLKREDPENF---MI 479
            .|.|.:.|....:|.       |      |.:|.|::.||:.|.  .:.|:|    |.|.   :.
Mosquito   430 YYQFSFDGDLNLVKRVLMLGSWP------GAMHADDIPYLWSVTDLTISPIL----PTNHARTVS 484

  Fly   480 ELLTRMWIEFAQKGDP-HNKNDEYLKGLNWPLYNAQDKGYLEIGNNLT--AKSGGFFLNRYQIWE 541
            ....|::..||:.|:| .|..|..|:...|....|....|::||::|.  ....|   .|..:|.
Mosquito   485 NRFVRLFTNFARFGNPTPNAVDTLLQSRQWQPVTAATVHYMDIGHDLVTGVNPNG---QRTAVWR 546

  Fly   542 DL 543
            ||
Mosquito   547 DL 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	165/561 (29%)
LOC1281452	XP_321363.5	None