Protein Alignment CG4757 and Gli

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: XP_061510245.1
• Gene: Gli / 1277780
• VectorBaseID: AGAMI1_001484
• Length: 973
• Species: Anopheles gambiae
• Alignment Length: 625
• Identity: 167/625 - (26%)
• Similarity: 259/625 - (41%)
• Gaps: 163/625 - (26%)

  Fly    23 VDTELGRVRG-----------ANL-------TSRLGVNFHAFRGIRYAEPPLGDLRFVNPQPVKP 69
            |.|..|:|:|           .||       ..|:......|.||.||.||..:.||..|:..:.
Mosquito   144 VTTNYGQVQGFMVYLYDNPDPKNLYRPWHSNVDRIMGKCSTFLGIPYALPPTHEGRFKPPRQHRG 208

  Fly    70 WSPKIFDASEDGPMCPQP------WDNMTDVSEDCLRLNVYTKDLKG----RRPVIVFLHPGGFY 124
            |  ::..|.:.||.||||      ...:.|:.||||.||:::.:.:.    |.||::::| ||.:
Mosquito   209 W--QLVQAVDYGPACPQPVQYTGATKGIRDMDEDCLYLNIFSPNTQAGVAQRYPVMIYIH-GGEF 270

  Fly   125 VFSGQSKYLAGPEHFMDR--DCVLVSLNYRLGSLGFLATGSKEAPGNAGLKDQVLALRWIQQHIQ 187
            |....:.:   |.|.:..  |.|:|:.|||||:||||:||.:.:|||.|:.||::|:||:.::|:
Mosquito   271 VRGASNTF---PGHMLAAFYDVVVVTFNYRLGALGFLSTGDENSPGNYGILDQIMAVRWVYENIE 332

  Fly   188 RFGGDPDSVTLLGYSAGSISVALHMLSPMSRGLFHRGICMSA---APYGPVKYK---DNDLQLAK 246
            .|.||.:|:||.|..||..|..|.|::|.::.:..|.|..|.   |.:..:..|   .|..::..
Mosquito   333 SFNGDRNSITLFGPGAGGASAGLLMVAPQTKDIVTRVIGQSGSALADWALIVDKWRAQNTSRVFA 397

  Fly   247 RQAGLLKCPQESIGEMVECMR--RKPYLDYVSTYNGMFE-----FGWNPVL-------------N 291
            :..|   |..|:..:||.|||  |..|    ...|..|.     |.|.|||             .
Mosquito   398 QNVG---CSIETSWKMVNCMRNGRSSY----ELGNAEFPPHVGLFPWGPVLENNFTFPGDSWYEG 455

  Fly   292 WRIVVEKDFGQERYLIESPFKTARRGDFHK-VALITGIT--EFEF-LSG------------AFFD 340
            |.   |:|:   .:|.|:|....||..|:: :..::|:|  |..| ::|            .|||
Mosquito   456 WS---ERDW---HFLAETPESLIRRRHFNRGLHYMSGVTLQEAAFVITGNKSLAPYFEVDERFFD 514

  Fly   341 LRNESIVNRYNRDWEHYASIALLLEQNSTQSRAASRVFREKYMPESLDKLEYPKSLKGMGE---- 401
            .:...:|.|||          ..|..|.|.....   :...|.|:       ||:...:.|
Mosquito   515 QKVRELVLRYN----------YTLNLNGTYEAIK---YMYTYWPD-------PKNTTFIREQYIN 559

  Fly   402 LLSDALIGVSFHRFLQLM-SPHTPIYTYLFRYKGRYTFLKNPDNQQTIG-------PVHHDELIY 458
            ||||.|......:.::|: ..:.|:|:|:.             |....|       .|.||...|
Mosquito   560 LLSDFLYRAPTDKLIKLLVEQNVPVYSYVM-------------NTTIEGLKLAEWCKVPHDIEHY 611

  Fly   459 LFHVGLLIPLL------KRE--------DPENFMIELLTRMWIEFAQKGDPHNKNDEYLKGLNWP 509
            |. .|  .|.:      :||        |.:..|.....:.:.:||:.|:|   ....:.||
Mosquito   612 LL-AG--APFMDVEFFPRRERFDRLMWTDNDRNMSHFFMKTYSDFARHGNP---TPTQVLGL--- 667

  Fly   510 LYNAQDKGYLEIGNNLTAKSGGFFLNRYQ----IWEDLFP 545
            .:.....|.|:..|..|..:....:|..|    .|.:..|
Mosquito   668 YFEKARNGELKYLNLNTTYNSTIMMNYRQTESAFWMEYLP 707

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	165/618 (27%)
Gli	XP_061510245.1	None