Protein Alignment CG4757 and Ces1g

DIOPT Version :9

• Sequence 1: NP_001262469.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_067431.2
• Gene: Ces1g / 12623
• MGIID: 88378
• Length: 565
• Species: Mus musculus
• Alignment Length: 586
• Identity: 173/586 - (29%)
• Similarity: 267/586 - (45%)
• Gaps: 123/586 - (20%)

  Fly     2 LMLFVVELLVLLASSSV----LSIEVDTELGRVRGANLT-SRLGVNFHAFRGIRYAEPPLGDLRF 61
            :.|..:.|:.|.|..|:    |...|.|..|:|.|..:| .........|.|:.:|:||||.|||
Mouse     1 MWLCALSLISLTACLSLGHPSLPPVVHTVHGKVLGKYVTLEGFSQPVAVFLGVPFAKPPLGSLRF 65

  Fly    62 VNPQPVKPWS---------PKIFDASEDGPMCPQPWDNMTDV-----SEDCLRLNVYT-KDL--K 109
            ..|:|.:|||         |..:...|......:.:.|...:     |||||.||:|| .||  .
Mouse    66 APPEPAEPWSFVKHTTSYPPLCYQNPEAALRLAELFTNQRKIIPHKFSEDCLYLNIYTPADLTQN 130

  Fly   110 GRRPVIVFLHPGGFYVFSGQSKYLAGPEHFMDRDCVLVSLNYRLGSLGFLATGSKEAPGNAGLKD 174
            .|.||:|::|.||. |..|.|.| .|....:..:.|:|.:.||||..||.:|..:.:.||.|..|
Mouse   131 SRLPVMVWIHGGGL-VIDGASTY-DGVPLAVHENVVVVVIQYRLGIWGFFSTEDEHSRGNWGHLD 193

  Fly   175 QVLALRWIQQHIQRFGGDPDSVTLLGYSAGSISVALHMLSPMSRGLFHRGICMSAAPYGPVKYKD 239
            ||.||.|:|.:|..|||:|.|||:.|.|||..||::.:|||:::.||||.|..|:..:.|..:..
Mouse   194 QVAALHWVQDNIANFGGNPGSVTIFGESAGGESVSVLVLSPLAKNLFHRAIAQSSVIFNPCLFGR 258

  Fly   240 NDLQLAKRQAGLLKCPQESIGEMVECMRRKPYLDYVSTYNGMFEFGWNPVLNWRIVVEKDFG--- 301
            ....|||:.|.|..|...:...||.|:|:|       |.:.:.|          :.::..||
Mouse   259 AARPLAKKIAALAGCKTTTSAAMVHCLRQK-------TEDELLE----------VSLKMKFGTVD 306

  Fly   302 -----QERY-----------LIESPFKTARRGDFHKVALITGITEFEF--LSGAFFDLRNESIVN 348
                 :|.|           |.::|.:......|:.|..:.||.:.||  :...|.|..
Mouse   307 FLGDPRESYPFLPTVIDGVLLPKAPEEILAEKSFNTVPYMVGINKHEFGWIIPMFLDFP------ 365

  Fly   349 RYNRDWEHYASIALLLEQNSTQSRAASRVFR--------EKYMPESLDK----LEYPKSLKGMG- 400
                          |.|:...|..|||.:::        ||.:|.:::|    .|.|.::..:.
Mouse   366 --------------LSERKLDQKTAASILWQAYPILNISEKLIPAAIEKYLGGTEDPATMTDLFL 416

  Fly   401 ELLSDALIGV------SFHRFLQLMSPHTPIYTYLFRYKGRYTFLKNPDNQQTIGPVHHDELIYL 459
            :|:.|.:.||      ..||     ....|  ||::.|:.|.:|:.:...|:.:|. |.|||..:
Mouse   417 DLIGDIMFGVPSVIVSRSHR-----DAGAP--TYMYEYQYRPSFVSDDRPQELLGD-HADELFSV 473

  Fly   460 FHVGLLIPLLKR--EDPENFMIELLTRMWIEFAQKGDPHNKNDEYLKGL-NWPLYNAQDKGYLEI 521
            :..    |.||.  .:.|..:.:::.:.|..||:.|:|:.      :|| :||.|: |.:|||:|
Mouse   474 WGA----PFLKEGASEEEINLSKMVMKFWANFARNGNPNG------EGLPHWPEYD-QKEGYLQI 527

  Fly   522 G 522
            |
Mouse   528 G 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_001262469.1	COesterase	15..540	CDD:278561	169/573 (29%)
		Aes	40..>204	CDD:223730	70/180 (39%)
Ces1g	NP_067431.2	COesterase	24..545	CDD:278561	167/563 (30%)
		Aes	<121..>239	CDD:223730	52/119 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832612
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	228	1.000	Inparanoid score	I3450
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.900