Protein Alignment CG4757 and Ces1d

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_579829.3
• Gene: Ces1d / 113902
• RGDID: 70896
• Length: 565
• Species: Rattus norvegicus
• Alignment Length: 568
• Identity: 173/568 - (30%)
• Similarity: 250/568 - (44%)
• Gaps: 123/568 - (21%)

  Fly    23 VDTELGRVRGANLTSRLGVNFHAFR-------GIRYAEPPLGDLRFVNPQPVKPWSPKIFDASED 80
            |:|..|:|.|..      ||...|.       ||.:|:||||.|||..|||.:||: .:.:.:..
  Rat    26 VNTVKGKVLGKY------VNLEGFAQPVAVFLGIPFAKPPLGSLRFAPPQPAEPWN-FVKNTTSY 83

  Fly    81 GPMCPQP----------WDNMTD-----VSEDCLRLNVYT-KDL--KGRRPVIVFLHPGGFYVFS 127
            .|||.|.          :.|..:     .|||||.||||| .||  ..|.||:|::|.||. |..
  Rat    84 PPMCSQDAVGGQVLSELFTNRKENIPLQFSEDCLYLNVYTPADLTKNSRLPVMVWIHGGGL-VVG 147

  Fly   128 GQSKY----LAGPEHFMDRDCVLVSLNYRLGSLGFLATGSKEAPGNAGLKDQVLALRWIQQHIQR 188
            |.|.|    |:..|     :.|:|::.||||..||.:||.:.:.||.|..|||.||.|:|.:|..
  Rat   148 GASTYDGQVLSAHE-----NVVVVTIQYRLGIWGFFSTGDEHSQGNWGHLDQVAALHWVQDNIAN 207

  Fly   189 FGGDPDSVTLLGYSAGSISVALHMLSPMSRGLFHRGICMSAAPYGPVKYKDNDLQLAKRQAGLLK 253
            |||:|.|||:.|.|||..||:..:|||:::.||||.|..|...........:...:|...|.|..
  Rat   208 FGGNPGSVTIFGESAGGFSVSALVLSPLAKNLFHRAISESGVVLTSALITTDSKPIANLIATLSG 272

  Fly   254 CPQESIGEMVECMRRKPYLDYVSTY------------NGMFEFGWNPVLNWRIVVEKDFGQERYL 306
            |...:...||.|:|:|...:.:.|.            |....:.:.|.:...:|:.|.  .|..|
  Rat   273 CKTTTSAVMVHCLRQKTEDELLETSLKLNLFKLDLLGNPKESYPFLPTVIDGVVLPKT--PEEIL 335

  Fly   307 IESPFKTARRGDFHKVALITGITEFEF-----------LSGAFFDLRN-ESIVNRYNRDWEHYAS 359
            .|..|.|        |..|.||.:.||           ||....|.:. :|::      |:.|.:
  Rat   336 TEKSFNT--------VPYIVGINKQEFGWIIPTLMGYPLSEGKLDQKTAKSLL------WKSYPT 386

  Fly   360 IALLLEQNSTQSRAASRVFREKYMPESLDKLEYPKSLKGM-GELLSDALIGV------SFHRFLQ 417
            :.:        |.....|..|||...:.|    |...|.: .:|::|.:.||      ..||
  Rat   387 LKI--------SEKMIPVVAEKYFGGTDD----PAKRKDLFQDLVADVMFGVPSVMVSRSHR--- 436

  Fly   418 LMSPHTPIYTYLFRYKGRYTFLKNPDNQQTIGPVHHDELIYLFHVGLLIPLLK--REDPENFMIE 480
              ....|.:.|.|.|:..:.....|   :|:...|.|||..:|.    .|.||  ..:.|..:.:
  Rat   437 --DAGAPTFMYEFEYRPSFVSAMRP---KTVIGDHGDELFSVFG----SPFLKDGASEEETNLSK 492

  Fly   481 LLTRMWIEFAQKGDPHNKNDEYLKGL-NWPLYNAQDKGYLEIGNNLTA 527
            ::.:.|..||:.|.|:.      .|| :||.|: |.:|||:||.:..|
  Rat   493 MVMKYWANFARNGSPNG------GGLPHWPEYD-QKEGYLKIGASTQA 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	173/568 (30%)
Ces1d	NP_579829.3	COesterase	22..545	CDD:395084	173/568 (30%)
		Prevents secretion from ER. /evidence=ECO:0000255	562..565