DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4757 and LOC107987423

DIOPT Version :9

Sequence 1:	NP_001262469.1	Gene:	CG4757 / 41330	FlyBaseID:	FBgn0027584	Length:	550	Species:	Drosophila melanogaster
Sequence 2:	XP_016885725.1	Gene:	LOC107987423 / 107987423	-ID:	-	Length:	286	Species:	Homo sapiens

Alignment Length:	322	Identity:	79/322 - (24%)
Similarity:	128/322 - (39%)	Gaps:	91/322 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   262 MVECMRRKPYLDYVSTYNGMFEFGWN---------PVLNWRIVVEKDFGQERYLIESPFKTARRG 317
            ||.|:|:|...:.:.|...|.....:         |:|...|       ....|:::|.:.....
Human     1 MVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPLLGTVI-------DGMLLLKTPEELQAER 58

  Fly   318 DFHKVALITGITEFEF------------LSGAFFDLRNE-SIVNRYNRDWEHYASIALLLE--QN 367
            :||.|..:.||.:.||            ||....|.:.. |::      |:.|..:.:..|  ..
Human    59 NFHTVPYMVGINKQEFGWLIPMQLMSYPLSEGQLDQKTAMSLL------WKSYPLVCIAKELIPE 117

  Fly   368 STQSRAASRVFREKYMPESLDKLEYPKSLKGMGELLSDALIGVSF------HRFLQLMSPHTPIY 426
            :|          |||:..:.|.:: .|.|  ..:|::|.:.||..      ||     ....|.|
Human   118 AT----------EKYLGGTDDTVK-KKDL--FLDLIADVMFGVPSVIVARNHR-----DAGAPTY 164

  Fly   427 TYLFRYKGRYTFLKNPDNQQTIGPVHHDELIYLFHVGLLIPLLKR--EDPENFMIELLTRMWIEF 489
            .|.|:|:..::....|   :|:...|.|||..:|..    |.||.  .:.|..:.:::.:.|..|
Human   165 MYEFQYRPSFSSDMKP---KTVIGDHGDELFSVFGA----PFLKEGASEEEIRLSKMVMKFWANF 222

  Fly   490 AQKGDPHNKNDEYLKGL-NWPLYNAQDKGYLEIGNNLTA------KSGGFFLNRYQIWEDLF 544
            |:.|:|:.      :|| :||.|| |.:|||:||.|..|      |...|       |.:||
Human   223 ARNGNPNG------EGLPHWPEYN-QKEGYLQIGANTQAAQKLKDKEVAF-------WTNLF 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_001262469.1	COesterase	15..540	CDD:278561	76/316 (24%)
CG4757	NP_001262469.1	Aes	40..>204	CDD:223730
LOC107987423	XP_016885725.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.010