Protein Alignment CG4757 and Ces1d

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_444430.2
• Gene: Ces1d / 104158
• MGIID: 2148202
• Length: 565
• Species: Mus musculus
• Alignment Length: 563
• Identity: 175/563 - (31%)
• Similarity: 257/563 - (45%)
• Gaps: 113/563 - (20%)

  Fly    23 VDTELGRVRG--ANL---TSRLGVNFHAFRGIRYAEPPLGDLRFVNPQPVKPWSPKIFDASEDGP 82
            |:|..|:|.|  .||   |..:.|    |.|:.:|:||||.|||..|||.:||| .:.:.:...|
Mouse    26 VNTVKGKVLGKYVNLEGFTQPVAV----FLGVPFAKPPLGSLRFAPPQPAEPWS-FVKNTTSYPP 85

  Fly    83 MCPQP----------WDNMTD-----VSEDCLRLNVYT-KDL--KGRRPVIVFLHPGGFYVFSGQ 129
            ||.|.          :.|..:     .|||||.||:|| .||  ..|.||:|::|.||. |..|.
Mouse    86 MCSQDAVGGQVLSELFTNRKENIPLQFSEDCLYLNIYTPADLTKNSRLPVMVWIHGGGL-VVGGA 149

  Fly   130 SKY--LAGPEHFMDRDCVLVSLNYRLGSLGFLATGSKEAPGNAGLKDQVLALRWIQQHIQRFGGD 192
            |.|  ||...|   .:.|:|::.||||..||.:||.:.:.||.|..|||.||||:|.:|..|||:
Mouse   150 STYDGLALSAH---ENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIANFGGN 211

  Fly   193 PDSVTLLGYSAGSISVALHMLSPMSRGLFHRGICMSAAPYGPVKYKDNDLQLAKRQAGLLKCPQE 257
            |.|||:.|.|||..||::.:|||:::.||||.|..|...........:...:|...|.|..|...
Mouse   212 PGSVTIFGESAGGFSVSVLVLSPLAKNLFHRAISESGVSLTAALITTDVKPIAGLVATLSGCKTT 276

  Fly   258 SIGEMVECMRRKPYLDYVSTY------------NGMFEFGWNPVLNWRIVVEKDFGQERYLIESP 310
            :...||.|:|:|...:.:.|.            |....:.:.|.:...:|:.|  ..|..|.|..
Mouse   277 TSAVMVHCLRQKTEDELLETSLKLNLFKLDLLGNPKESYPFLPTVIDGVVLPK--APEEILAEKS 339

  Fly   311 FKTARRGDFHKVALITGITEFEF-----------LSGAFFDLRN-ESIVNRYNRDWEHYASIALL 363
            |.|        |..|.||.:.||           |:....|.:. .|::      |:.|.::.:
Mouse   340 FST--------VPYIVGINKQEFGWIIPTLMGYPLAEGKLDQKTANSLL------WKSYPTLKI- 389

  Fly   364 LEQNSTQSRAASRVFREKYMPESLDKLEYPKSLKGMGELLSDALIGV------SFHRFLQLMSPH 422
                   |.....|..|||: ...|.|...|.|  ..:|::|.:.||      ..||       .
Mouse   390 -------SENMIPVVAEKYL-GGTDDLTKKKDL--FQDLMADVVFGVPSVIVSRSHR-------D 437

  Fly   423 TPIYTYLFRYKGRYTFLKNPDNQQTIGPVHHDELIYLFHVGLLIPLLK--REDPENFMIELLTRM 485
            ....||::.::.|.:|:.....:..||. |.||:..:|.    .|.||  ..:.|..:.:::.:.
Mouse   438 AGASTYMYEFEYRPSFVSAMRPKAVIGD-HGDEIFSVFG----SPFLKDGASEEETNLSKMVMKF 497

  Fly   486 WIEFAQKGDPHNKNDEYLKGL-NWPLYNAQDKGYLEIGNNLTA 527
            |..||:.|:|:.      .|| :||.|: |.:|||:||.:..|
Mouse   498 WANFARNGNPNG------GGLPHWPEYD-QKEGYLKIGASTQA 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	175/563 (31%)
Ces1d	NP_444430.2	COesterase	22..545	CDD:395084	175/563 (31%)
		Prevents secretion from ER. /evidence=ECO:0000255	562..565