Protein Alignment CG4757 and Ces2a

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_598721.1
• Gene: Ces2a / 102022
• MGIID: 2142491
• Length: 558
• Species: Mus musculus
• Alignment Length: 578
• Identity: 178/578 - (30%)
• Similarity: 276/578 - (47%)
• Gaps: 93/578 - (16%)

  Fly     9 LLVLL----ASSSVLSIEVDTELGRVRGANL---TSRLGVNFHAFRGIRYAEPPLGDLRFVNPQP 66
            ||:||    ...|...|. :|..|:|||:.:   .::.||  |||.||.:|:||:|.|||..|:.
Mouse    17 LLLLLQHVHGQDSASPIR-NTHRGQVRGSFVHVKDTKSGV--HAFLGIPFAKPPVGLLRFAPPED 78

  Fly    67 VKPWSPKIFDASEDGPMCPQPWD--NMTD------------VSEDCLRLNVYTKD--LKGRR-PV 114
            .:||| .:.|.:....||.|| |  |:.|            :|||||.||:||..  .:|.. ||
Mouse    79 PEPWS-GVRDGTSQPAMCLQP-DIMNLEDAKEMNLILPPISMSEDCLYLNIYTPTHAQEGSNLPV 141

  Fly   115 IVFLHPGGFYVFSGQ----SKYLAGPEHFMDRDCVLVSLNYRLGSLGFLATGSKEAPGNAGLKDQ 175
            :|::|.||..|.|..    || ||..|     :.|:|::.||||.|||.:||.:.|.||.|..||
Mouse   142 MVWIHGGGLVVGSASMNDVSK-LAATE-----EIVIVAIQYRLGVLGFFSTGDQHARGNWGYLDQ 200

  Fly   176 VLALRWIQQHIQRFGGDPDSVTLLGYSAGSISVALHMLSPMSRGLFHRGICMSAAPYGPVKYKDN 240
            |.||||:|::|..|||:.|.||:.|.|||..||:.|:|||||:||||..|..|.....|....|.
Mouse   201 VAALRWVQKNIAYFGGNRDRVTIFGVSAGGTSVSSHILSPMSKGLFHGAIMQSGVALLPDLISDT 265

  Fly   241 DLQLAKRQAGLLKCPQESIGEMVECMRRKPYLDYVSTYNGMFEFGWNPVLNWRIVVEKDFGQERY 305
            ...:.|..|.|..|.......::.|:|.|...: :...|.:|:.  .|.     ||:.:|
Mouse   266 SEVVYKTVANLSGCEATDSEALIHCLRAKSKQE-ILAINQVFKM--IPA-----VVDGEF----- 317

  Fly   306 LIESPFKTARRGDFHKVALITGITEFEFLSGAFFDLRNESIVNRYNRDWEHYASIALLLEQNSTQ 370
            |.:.|.:.....|||.|..|.|:...|...|....:..:.|:....|:     ::..:|:..:.:
Mouse   318 LPKHPQELLTSMDFHPVPSIIGVNTDECGWGVPMFMGLDHIIKNITRE-----TLPAVLKNTAAR 377

  Fly   371 SR---AASRVFREKYMPESLDKLEYPKSLKG-MGELLSDALIGVSFHRFLQLMSPHTPIYTYLFR 431
            ..   ..|.:..|:||.::.|    |::|:. ..|:|.|.:..:...:.........|:|.|.|:
Mouse   378 MMLPPECSHLLVEEYMGDTED----PETLQAQFREMLGDFMFVIPALQVAHFQRSQAPVYFYEFQ 438

  Fly   432 YKGRYTFLKN--PDNQQTIGPVHHDELIYLFHVGLLIPLLKREDPENFMIELLTRMWIEFAQKGD 494
            :..  :|:|:  |.:   :...|.|::.::|...|....|...:.|..:..::.:.|..||:.|:
Mouse   439 HLS--SFIKHVRPSH---VKADHGDDVAFVFGSYLWDMNLDLTEEEELLKRMMMKYWANFARNGN 498

  Fly   495 PHNKNDEYLKGL-NWPLYNAQDKGYLE------IGNNLTAKSGGFFLNRYQIWEDLFP 545
            |::      :|| :||:.: .|:.||:      :|..|.|:       |.|.|....|
Mouse   499 PNS------EGLPSWPVLD-HDEQYLQLDTQPAVGRALKAR-------RLQFWTKTLP 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	171/556 (31%)
Ces2a	NP_598721.1	COesterase	30..537	CDD:395084	171/558 (31%)