Protein Alignment CG4757 and Ces2

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_001177298.1
• Gene: Ces2 / 100910144
• RGDID: 6504334
• Length: 561
• Species: Rattus norvegicus
• Alignment Length: 554
• Identity: 161/554 - (29%)
• Similarity: 253/554 - (45%)
• Gaps: 79/554 - (14%)

  Fly    25 TELGRVRGA---NLTSRLGVNFHAFRGIRYAEPPLGDLRFVNPQPVKPWSPKIFDASEDGPMCPQ 86
            |..|:|:|.   ...::.||  |.|.||.:|:||:|.|||..|:|.:||| .:.||:....||.|
  Rat    38 THTGQVQGKLDHVKDTKAGV--HTFLGIPFAKPPVGPLRFAPPEPPEPWS-GVRDATSQPAMCLQ 99

  Fly    87 PWDNMTDV--------------SEDCLRLNVYT-------KDLKGRRPVIVFLHPGGFYVFSGQS 130
            ..|.:.:|              |||||.||||.       .:|    ||:|::|.|...|  |.:
  Rat   100 NLDILDEVGLLDMKMILSSISMSEDCLYLNVYAPAHAREGSNL----PVMVWIHGGALVV--GMA 158

  Fly   131 KYLAGPEHFMDRDCVLVSLNYRLGSLGFLATGSKEAPGNAGLKDQVLALRWIQQHIQRFGGDPDS 195
            ....|....::.|.|:|::.||||.|||.:||.:.|.||.|..|||.||||:||:|..|||:|:.
  Rat   159 SMYDGSLLTVNEDLVVVTIQYRLGVLGFFSTGDEHARGNWGYLDQVAALRWVQQNIAHFGGNPNR 223

  Fly   196 VTLLGYSAGSISVALHMLSPMSRGLFHRGICMSAAPYGPVKYKDNDLQLAKRQAGLLKCPQESIG 260
            ||:.|.|||..||:.|::||||:||||..|..|.....|....:....::...|.|..|......
  Rat   224 VTIFGESAGGTSVSSHVISPMSQGLFHGAIMESGVALLPDLISETSETVSTTVAKLSGCEAMDSE 288

  Fly   261 EMVECMRRKPYLDYVSTYNGMFEFGWNPVLNWRIVVEKDFGQERYLIESPFKTARRGDFHKVALI 325
            .:|.|:|.|...: :...|.:|:.  .|.     ||:.:|     |...|.:.....|||.|..|
  Rat   289 ALVRCLRAKSGAE-ILVINKVFKM--IPA-----VVDGEF-----LPRHPKELLASEDFHPVPSI 340

  Fly   326 TGITEFEFLSGAFFDLRNESIVNRYNRDWEHYASIALLLEQNSTQSR---AASRVFREKYMPESL 387
            .|:...|:.......:....|:...:|:     ::..:|:..:.|..   ....:..|:||..:.
  Rat   341 IGVNTDEYCCTIPMVMGTAQIIKELSRE-----NLQAVLKDTAAQMMLPPECGDLLMEEYMGNTD 400

  Fly   388 D----KLEYPKSLKGMGELLSDALIGVSFHRFLQLMSPHTPIYTYLFRYKGRYTFLKNPDNQQTI 448
            |    :::|.       |::.|.|..:...:.......|.|:|.|.|::...|.....|.:   :
  Rat   401 DSQTLQIQYT-------EMMGDFLFVIPALQVAHFQRSHAPVYFYEFQHAPSYFKNVRPPH---V 455

  Fly   449 GPVHHDELIYLFHVGLLIPLLKRE--DPENFMIELLTRMWIEFAQKGDPHNKNDEYLKGLNWPLY 511
            ...|.||:.::|  |.....:|.:  :.|..:...:.:.|..||::|:|:::...|     ||..
  Rat   456 KADHADEVPFVF--GSFFSGMKLDFTEEERLLSRRMMKYWANFARQGNPNSEGLPY-----WPAL 513

  Fly   512 NAQDKGYLEIGNNLTAKSGGFFLNRYQIWEDLFP 545
            : .|:.||::..: .|........|.|.|....|
  Rat   514 D-HDEQYLQLDTH-PAVDRALKARRLQFWTKTLP 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	159/547 (29%)
Ces2	NP_001177298.1	COesterase	32..540	CDD:395084	159/547 (29%)