DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4757 and tg

DIOPT Version :9

Sequence 1:	NP_001262469.1	Gene:	CG4757 / 41330	FlyBaseID:	FBgn0027584	Length:	550	Species:	Drosophila melanogaster
Sequence 2:	NP_001316486.1	Gene:	tg / 100492021	XenbaseID:	XB-GENE-6073495	Length:	2780	Species:	Xenopus tropicalis

Alignment Length:	617	Identity:	155/617 - (25%)
Similarity:	245/617 - (39%)	Gaps:	159/617 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 FVVELLVLLASSSVLSIEVDTELGR----VRGANLTSRLGVNFHAFRGIRYAEPPLGDLRFVNPQ 65
            |:....|....|:.::|...|.||:    |.|:|:.     |...|.||.||.||:|..||..||
Frog  2204 FIFRRKVRPPPSTSVAIPQGTLLGKSEAVVIGSNIK-----NVVQFLGIPYAAPPVGVYRFSPPQ 2263

  Fly    66 PVKPWSPKIFDASEDGPMCPQPWD---NMTDVSEDCLRLNVYTKDLKGRRPVIVFLHPGGFYVFS 127
            ||. |:.: ::|:.....|.||.|   ..:.|.||||.|||:.....|....::      .|..:
Frog  2264 PVN-WTGE-WNATYSRASCLQPGDGKAQYSSVGEDCLYLNVFVPQHAGTNAAVL------LYFHN 2320

  Fly   128 GQSKYLAGPEHFMD-------RDCVLVSLNYRLGSLGFLATGSKEAP-GNAGLKDQVLALRWIQQ 184
            ..|.|....:.|:|       .:.|:|:..||:|..|||:...:.|| ||.||.|||.||:|:|:
Frog  2321 SPSDYSEKGQTFIDGSYLAAIGNIVVVTAGYRVGVFGFLSNTGETAPSGNWGLLDQVAALKWVQE 2385

  Fly   185 HIQRFGGDPDSVTLLGYSAGSISVALHMLSPMSRGLFHRGICMSAAPYGPVKYKDNDLQLAKRQA 249
            :|..|||||..:::....||:...::|.:.|..: ||.|.:.|..:.:.|:.....  :.||.|.
Frog  2386 NIAYFGGDPTLISIAADRAGADISSIHTIVPEGK-LFRRALLMGGSAFSPMMVTSE--KRAKEQV 2447

  Fly   250 GLLKCPQESIGEMVECMRRKPYLDYVSTYNGMFEFGWN-----------PVLNWRIVVEKDFGQE 303
                   |.:...|||.....  |.::...|:.....|           |...|..:|:|
Frog  2448 -------EFLAAEVECSSSNK--DLLTCLRGVDAGALNAAQTKLLAQRGPFQTWGPIVDK----- 2498

  Fly   304 RYLIESPFKTARRGDFHKVALITGITEFEFLSGAFFDLRNESIVNRYNRDWEHYASIALLLEQNS 368
            .|:.|:|.:..::..|.|:.|:.|.:|.:.|      :.....:.|:                ..
Frog  2499 LYVKETPSRMLKQKKFQKIDLLIGSSELDGL------ISRAKAIKRF----------------EE 2541

  Fly   369 TQSRAASRVFREKYMPESLDKLEYPKSLKGMGELLSDALIGVSFHRFLQLMSPHTPIYTYLFR-- 431
            ||.|              :||..:.::|:       ::|.||..:..||    ...::.|...
Frog  2542 TQGR--------------VDKTAFYQALQ-------NSLGGVEANSLLQ----EAAVWFYSLEHS 2581

  Fly   432 ---YKGRYTFLKNPDNQQTIG-PV-----HHDE----LIYLFHV---------GLLIPLLKRED- 473
               |.|....|:.......|. ||     |..|    .|||:||         ||.:|    ||
Frog  2582 SDDYTGFSKALEKATRDHFIACPVIKMAKHWAENSKGNIYLYHVPDTLSQSSSGLDLP----EDV 2642

  Fly   474 -----------------PENFMIELLTRMWI-EFAQKGDPHNKNDEYLKGLN-----WPLYNAQD 515
                             .|..::.|....:: .|.:.|:| |...::|:.::     ||:|.|..
Frog  2643 IRAFGLPFHTNYKNQFSSEEQILSLKIMQYVSNFVRTGNP-NFPYKFLRRISKELPAWPMYLAHS 2706

  Fly   516 KG--YLEIGNNLTAKSGGFFLNRYQIWEDLFP 545
            .|  |.|..::|| .:.|...:....|.|..|
Frog  2707 NGTNYKEFSSSLT-NNQGLKNSECSFWNDYIP 2737

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_001262469.1	COesterase	15..540	CDD:278561	150/600 (25%)
CG4757	NP_001262469.1	Aes	40..>204	CDD:223730	62/174 (36%)
tg	NP_001316486.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910