Protein Alignment CG4757 and nlgn4x

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: XP_017946613.1
• Gene: nlgn4x / 100329189
• XenbaseID: XB-GENE-6036018
• Length: 833
• Species: Xenopus tropicalis
• Alignment Length: 632
• Identity: 166/632 - (26%)
• Similarity: 270/632 - (42%)
• Gaps: 136/632 - (21%)

  Fly     9 LLVLLASSSVLSIEVD---------TELGRVRGANLTSRLGV--NFHAFRGIRYAEPPLGDLRFV 62
            ||:.:|:.:|....||         |..|::||......:.:  ....:.|:.||.||.|:.||.
 Frog    25 LLLWIAALAVRFTIVDCQAQHPIVPTNYGKIRGTRTPLPIEILGPVEQYLGVPYASPPTGERRFQ 89

  Fly    63 NPQPVKPWSPKIFDASEDGPMCPQPWDN----------------------MTDVSEDCLRLNVY- 104
            .|:|...|: .|.:|::..|:|||..|.                      :.|.:||||.||:|
 Frog    90 PPEPPSSWT-GIKNATQFAPVCPQFLDERSLLNDMLPIWFTANLDTVVSYVQDQNEDCLYLNIYV 153

  Fly   105 -------TK------------------DLKGRRPVIVFLHPGGFYVFSGQSKYLAGPEHFMDRDC 144
                   ||                  |...::||:|::| ||.|: .|....:.|.......:.
 Frog   154 PTEDGATTKKQADDIANNDRGEDEDIHDPNNKKPVMVYIH-GGSYM-EGTGNMIDGSILASHGNV 216

  Fly   145 VLVSLNYRLGSLGFLATGSKEAPGNAGLKDQVLALRWIQQHIQRFGGDPDSVTLLGYSAGSISVA 209
            :::::|||||.||||:||.:.|.||.||.||:.|||||:::|..|||||..||:.|..||:..|:
 Frog   217 IVITVNYRLGVLGFLSTGDQAAKGNYGLLDQIQALRWIEENIGAFGGDPKRVTIFGSGAGASCVS 281

  Fly   210 LHMLSPMSRGLFHRGICMS-------AAPYGPVKYKDNDLQLAKRQAGLLKCPQESIGEMVECMR 267
            |..||..|.|||.:.|..|       |..|.|.||       .:..|..:.|......::|||:|
 Frog   282 LLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKY-------TRILADKVGCDMLDTIDLVECLR 339

  Fly   268 RKPYLDYV--STYNGMFEFGWNPVLNWRIVVEKDFGQERYLIESPFKTARRGDFHKVALITGITE 330
            .|.|.:.:  |.....:...:.||::..::.:    ..:.|:|       :|:|....::.|:.:
 Frog   340 DKNYKELIQQSITPATYHIAFGPVIDGDVIPD----DPQILME-------QGEFLNYDIMLGVNQ 393

  Fly   331 FEFLSGAFFD--LRNESIVNRYNRDWEHYASIALLLEQNSTQSRAASRVFRE--KYMPESLDKLE 391
            .|.|.  |.|  :.||..|:..:.|:    |::..:: |...........||  |:|.......|
 Frog   394 GEGLK--FVDGMVDNEDGVSLSDFDF----SVSNFVD-NLYGYPEGKDTLRETIKFMYTDWADKE 451

  Fly   392 YPKS-LKGMGELLSD------ALIGVSFH-RFLQLMSPHTPIYTYLFRYKGRYTFLKNPDNQQTI 448
            .|:: .|.:..|.:|      |:.....| |:      .:|.|.|.|     |...::.......
 Frog   452 NPETRRKTLVALFTDHQWVAPAVATADLHARY------GSPTYFYAF-----YHHCQSEMKPTWA 505

  Fly   449 GPVHHDELIYLFHVGLLIP--LLKREDPEN--FMIELLTRMWIEFAQKGDP-----------HNK 498
            ...|.||:.|:|.:.::.|  |......:|  .:..::...|..||:.|||           |.|
 Frog   506 DSAHGDEVPYVFGIPMIGPTELFNCNFSKNDVMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTK 570

  Fly   499 NDEYLKGLNWPLYNAQDKGYLEIGNNLTAKSGGFFLNRYQIWEDLFP 545
            .:.: :.:.|..|:.:|:.||.||.....:. .:...:...|.:|.|
 Frog   571 PNRF-EEVAWSKYDPKDQLYLHIGLKPRVRD-HYRATKVAFWLELVP 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	159/614 (26%)
nlgn4x	XP_017946613.1	COesterase	46..610	CDD:395084	157/604 (26%)