Protein Alignment CG4757 and nlgn3

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: XP_012823589.1
• Gene: nlgn3 / 100329188
• XenbaseID: XB-GENE-977261
• Length: 843
• Species: Xenopus tropicalis
• Alignment Length: 672
• Identity: 175/672 - (26%)
• Similarity: 275/672 - (40%)
• Gaps: 180/672 - (26%)

  Fly     2 LMLFVVELL--VLLASSSVLSIEVDTELGRVRGAN--LTSRLGVNFHAFRGIRYAEPPLGDLRFV 62
            |:|:|:.:.  ||.:.:.|.|..|:|..|::||..  |.|.:......:.|:.||.||:|:.||:
 Frog    15 LVLWVLSVTSRVLSSHAQVYSQTVNTHYGKLRGTRVPLPSEILGPVDQYLGVPYAAPPVGEKRFL 79

  Fly    63 NPQPVKPWSPKIFDASEDGPMCPQPWDN---------------------MTDVSEDCLRLNVY-- 104
            .|:|...|| .|.:|:...|:|||...|                     :.:.|||||.||:|
 Frog    80 PPEPPPSWS-GIRNATHFSPVCPQNIQNAVPDIMMPVWFTSNLDTVTGYLQEQSEDCLYLNIYVP 143

  Fly   105 TKDLK-------------------------------------------GRRPVIVFLHPGGFYVF 126
            |:|:|                                           |.:||:|::| ||.|:
 Frog   144 TEDVKRISKECVRKPNKKICRKGGPSAKKQGEELSDNDEDEEGDIRDTGAKPVMVYIH-GGSYM- 206

  Fly   127 SGQSKYLAGPEHFMDRDCVLVSLNYRLGSLGFLATGSKEAPGNAGLKDQVLALRWIQQHIQRFGG 191
            .|....:.|.......:.|:::||||:|.||||:||.:.|.||.||.||:.||||:.:::..|||
 Frog   207 EGSGNMIDGSVLASYGNVVVITLNYRVGVLGFLSTGDQAAKGNYGLLDQIQALRWVSENVAFFGG 271

  Fly   192 DPDSVTLLGYSAGSISVALHMLSPMSRGLFHRGICMS-------AAPYGPVKYKDNDLQLAKRQA 249
            ||..:|:.|...|:..|:|..||..|.|||.|.|..|       |..|.||||    .:|...:.
 Frog   272 DPHRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQPVKY----TRLLAEKV 332

  Fly   250 GLLKCPQESIGEMVECMRRKPYLDYV--STYNGMFEFGWNPVLNWRIVVEKDFGQERYLIESPFK 312
            |   |......:||:|:|:|...:.|  ......:...:.||::..::.           :.|..
 Frog   333 G---CNVLDTVDMVDCLRQKSAKELVEQDIQPARYHVAFGPVIDGDVIP-----------DDPEI 383

  Fly   313 TARRGDFHKVALITGITEFEFL-------------SGAFFDLRNESIV-NRYNRDWEHYASIALL 363
            ...:|:|....::.|:.:.|.|             ||:.||....:.| |.|...
 Frog   384 LMEQGEFLNYDIMLGVNQGEGLKFVENVVDAEDGVSGSDFDYSVSNFVDNLYGYP---------- 438

  Fly   364 LEQNSTQSRAASRVFRE--KYMPESLDKLEYPKS-LKGMGELLSD------ALIGVSFH-RFLQL 418
             |...|        .||  |:|.......:.|:: .|.:..|.:|      :::....| |:
 Frog   439 -EGKDT--------LRETIKFMYTDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLHARY--- 491

  Fly   419 MSPHTPIYTYLFRYKGRYTFLKNPDNQQTIGPVHHDELIYLFHVGLLIPLLKRED--PENF---- 477
               .:|.|.|.|     |...::..........|.||:.|:|.|    |::...|  |.||
 Frog   492 ---GSPTYFYAF-----YHHCQSLMKPAWADAAHGDEVPYVFGV----PMVGPTDLFPCNFSKND 544

  Fly   478 --MIELLTRMWIEFAQKGDP-----------HNKNDEYLKGLNWPLYNAQDKGYLEIGNNLTAKS 529
              :..::...|..||:.|||           |.|.:.: :.:.|..||.:|:.||.||.....:.
 Frog   545 VMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKANRF-EEVAWSKYNPRDQLYLHIGLKPRVRD 608

  Fly   530 GGFFLNRYQIWEDLFP-LSSFH 550
             .:...:...|:.|.| |.:.|
 Frog   609 -HYRATKVAFWKHLVPHLYNLH 629

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	164/639 (26%)
nlgn3	XP_012823589.1	COesterase	35..618	CDD:395084	164/639 (26%)