Protein Alignment CG4757 and nlgn1

DIOPT Version :9

• Sequence 1: NP_001262469.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: XP_017949302.2
• Gene: nlgn1 / 100329186
• XenbaseID: XB-GENE-6041753
• Length: 859
• Species: Xenopus tropicalis
• Alignment Length: 696
• Identity: 168/696 - (24%)
• Similarity: 264/696 - (37%)
• Gaps: 243/696 - (34%)

  Fly    12 LLASSSVLSIEVD-------TELGRVRG--ANLTSRLGVNFHAFRGIRYAEPPLGDLRFVNPQPV 67
            ||..::|.|.::|       |..|:|||  ..|.:.:......|.|:.||.||:|:.||..|:|.
 Frog    37 LLHIATVRSQKLDDVDPVVLTTYGKVRGFKKELNNEILGPVVQFLGVPYAAPPIGERRFQPPEPP 101

  Fly    68 KPWSPKIFDASEDGPMCPQ-------------PW--DNM-------TDVSEDCLRLNVY--TKDL 108
            ..|. .|.::::..|:|||             .|  :|:       .|.|||||.||:|  |:|:
 Frog   102 TMWG-DIKNSTQFAPVCPQNIVGGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDV 165

  Fly   109 K--------------------------------------------GRRPVIVFLHPGGFY----- 124
            |                                            |.:||:|::| ||.|
 Frog   166 KRISKECARKPGKKICRKEGPLTKKQTDDLGDNEGAEDEDIRDSGGPKPVMVYIH-GGSYMEGTG 229

  Fly   125 -VFSGQSKYLAGPEHFMDRDCVLVSLNYRLGSLGFLATGSKEAPGNAGLKDQVLALRWIQQHIQR 188
             ||.|......|       :.:::::|||||.||||:||.:.:.||.||.|.:.||||..::|..
 Frog   230 NVFDGSVLASYG-------NVIVITVNYRLGVLGFLSTGDQASKGNYGLLDLIQALRWTSENIGF 287

  Fly   189 FGGDPDSVTLLGYSAGSISVALHMLSPMS---------RGLFHRGICMS-------AAPYGPVKY 237
            |||||..:|:.|..||:..|.|..||..|         :|||.|.|..|       |..:.|.||
 Frog   288 FGGDPLRITVFGSGAGASCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKY 352

  Fly   238 KDNDLQLAKRQAGLLKCPQESIGEMVECMRRKPYLDYVSTYNGMFEFGWNPVLNWRIVVEKDFGQ 302
                   |:..|..:.|.....||:|||:::|||                     |.:|::|...
 Frog   353 -------ARILATKVGCNMSDSGELVECLQKKPY---------------------RELVDQDIQP 389

  Fly   303 ERYLI------------ESPFKTARRGDFHKVALITGI---------------------TEFEFL 334
            .||.|            :.|.....:|:|....::.|:                     ::|:|.
 Frog   390 VRYHIAFGPVIDGDVIPDDPQVLMEQGEFLNYDIMLGVNQGEGLKFVESTVDHEDGVSSSDFDFA 454

  Fly   335 SGAFF----------DLRNESIVNRYNRDWEHYASIALLLEQNSTQSRAASRVFREKYMPESLDK 389
            ...|.          |:..|:|...|. ||         .::|:.::|.
 Frog   455 VSNFVDNLYGYTEGKDILRETIKFMYT-DW---------ADRNNPETRR---------------- 493

  Fly   390 LEYPKSLKGM---GELLSDALIGVSFHRFLQLMSPHTPIYTYLFRYKGRYTFLKNPDNQQTIGPV 451
                |:|..:   .:.::.|:.....|     .:..:|.|.|.|     |...:...........
 Frog   494 ----KTLLALFTDHQWVAPAVATADLH-----SNFGSPTYFYAF-----YHHCQTDQVPAWADAS 544

  Fly   452 HHDELIYLFHVGLLIPLLKREDPENF------MIELLTRMWIEFAQKGDP-----------HNKN 499
            |.||:.|:|.:.::.|  ....|.||      :..::...|..||:.|||           |.|.
 Frog   545 HGDEIPYVFGIPMIGP--TELFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKP 607

  Fly   500 DEYLKGLNWPLYNAQDKGYLEIGNNLTAKSGGFFLNRYQIWEDLFP 545
            :.: :.:.|..|:.:|:.||.||.....|. .:...:..:|.:|.|
 Frog   608 NRF-EEVAWTRYSQKDQLYLHIGLKPRVKE-HYRATKVNLWLELVP 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_001262469.1	COesterase	15..540	CDD:278561	163/686 (24%)
		Aes	40..>204	CDD:223730	71/237 (30%)
nlgn1	XP_017949302.2	COesterase	52..646	CDD:395084	160/674 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910