Protein Alignment CG4757 and nlgn4xb

DIOPT Version :10

• Sequence 1: NP_650043.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_001159809.1
• Gene: nlgn4xb / 100147967
• ZFINID: ZDB-GENE-100309-1
• Length: 795
• Species: Danio rerio
• Alignment Length: 604
• Identity: 168/604 - (27%)
• Similarity: 269/604 - (44%)
• Gaps: 133/604 - (22%)

  Fly    21 IEVDTELGRVRGAN--LTSRLGVNFHAFRGIRYAEPPLGDLRFVNPQPVKPWSPKIFDASEDGPM 83
            |.|.|..|::||..  |.|.:......|.|:.||..|.|:.||..|:|...| |.|.:|::..|:
Zfish    23 ITVTTNYGKLRGLRVALPSEILGPVEQFLGVPYAMAPTGERRFQAPEPPLSW-PGIRNATQFAPV 86

  Fly    84 CPQPWDN---MTDV-------------------SEDCLRLNVY------TKDLKGRRPVIVFLHP 120
            |||..::   :||:                   |||||.||:|      |:|..|.:||:|::|
Zfish    87 CPQFLEDRLLLTDMLPVWFTANLDTVATYVHDQSEDCLYLNIYVPTEEETQDDAGLKPVMVYIH- 150

  Fly   121 GGFYVFSGQSKYLAGPEHFMDRDCVLVSLNYRLGSLGFLATGSKEAPGNAGLKDQVLALRWIQQH 185
            ||.|| .|....:.|.......:.::|::|||||.||||:||.:.|.||.||.||:.||||::::
Zfish   151 GGSYV-EGTGNMIDGSVLASYGNVIVVTVNYRLGVLGFLSTGDQAAKGNYGLLDQIQALRWVKEN 214

  Fly   186 IQRFGGDPDSVTLLGYSAGSISVALHMLSPMSRGLF-----HRGICMS--AAPYGPVKYKDNDLQ 243
            ||.|.|||:.||:.|..||:..|:|..||..|..||     |.|..:|  |..|.|.||    .:
Zfish   215 IQSFSGDPERVTIFGSGAGASCVSLLTLSHYSEDLFQKAIIHSGTALSSWAVNYQPAKY----TR 275

  Fly   244 LAKRQAGLLKCPQESIGEMVECMRRKPYLDYV--STYNGMFEFGWNPVLNWRIVVEKDFGQERYL 306
            |...:.|   |.::...|::||::.|.|.:.:  :.....:...:.||::..::.:    ..:.|
Zfish   276 LLAEKVG---CNEDDTLELIECLQSKNYKELIEQNITPAKYHIAFGPVIDGDVIPD----DPQIL 333

  Fly   307 IESPFKTARRGDFHKVALITGITE---FEFLSGAFFDLRNESIVNRYNRDWEHYASIALLLEQNS 368
            :|       :|:|....::.|:.:   ::|:.|.   |.:|..|.  :.|:|.
Zfish   334 ME-------QGEFLNYDIMLGVNQGEGYKFVDGI---LDSEDRVT--SNDFEF------------ 374

  Fly   369 TQSRAASRVFREKY-MPESLDKLEYPKSLKGM---------GELLSDALIGV-SFHRFLQLMSP- 421
                |.|......| .||..|.|.  :::|.|         .|:....|:.: :.|   |.::|
Zfish   375 ----AISEFVDHLYGYPEGKDTLR--ETIKFMYTDWADRENPEMRRKTLVALFTDH---QWVAPA 430

  Fly   422 ------H----TPIYTYLFRYKGRYTFLKNPDNQQTIGPVHHDELIYLFHVGLLIP--LLKREDP 474
                  |    :|.|.|.|     |...::..........|.|||.|:|.:.::.|  |......
Zfish   431 VATADLHAQYGSPTYFYAF-----YHHCQSDMKPAWADSSHGDELPYVFGIPMIGPTDLFNCNFS 490

  Fly   475 EN--FMIELLTRMWIEFAQKGDP-----------HNKNDEYLKGLNWPLYNAQDKGYLEIGNNLT 526
            :|  .:..::...|..||:.|||           |.|.:.: :.:.|..||.:|:.||.||....
Zfish   491 KNDIMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRF-EEVAWSKYNPKDQLYLHIGLKPR 554

  Fly   527 AKSGGFFLNRYQIWEDLFP 545
            .:. .:...:...|.:|.|
Zfish   555 VRD-HYRATKIAFWLELVP 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_650043.1	COesterase	20..540	CDD:395084	165/597 (28%)
nlgn4xb	NP_001159809.1	COesterase	24..567	CDD:395084	164/596 (28%)