Protein Alignment CG4757 and ces3.1

DIOPT Version :9

• Sequence 1: NP_001262469.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_001120019.1
• Gene: ces3.1 / 100144981
• XenbaseID: XB-GENE-6467140
• Length: 557
• Species: Xenopus tropicalis
• Alignment Length: 573
• Identity: 177/573 - (30%)
• Similarity: 256/573 - (44%)
• Gaps: 120/573 - (20%)

  Fly    27 LGRVRGANLTSRLGVNFHAFRGIRYAEPPLGDLRFVNPQPVKPWSPKIFDASEDGPMCPQPWDNM 91
            ||:..||..|.||   .|.|.|:.:|:||:|.|||..|||.:||| .:.:|:...|||.|..:.|
 Frog    35 LGKTVGAKETDRL---VHVFMGVPFAKPPIGPLRFEAPQPPEPWS-SVREATAPSPMCLQDKEVM 95

  Fly    92 -------------TDVSEDCLRLNVYTKDLKGRR---PVIVFLHPGGFYVFSGQSKYLAGPEHFM 140
                         :.||||||.|||:|...||..   ||:||:|.||..:  |.:....|.....
 Frog    96 ELLADFFKAKFDFSRVSEDCLYLNVFTPADKGENPGLPVMVFIHGGGLAI--GGASMFEGSALSA 158

  Fly   141 DRDCVLVSLNYRLGSLGFLATGSKEAPGNAGLKDQVLALRWIQQHIQRFGGDPDSVTLLGYSAGS 205
            ..:.|:||:.||||.:|||:||.||..||.|..|||.||:|::.:|:.|||||.|||:.|.|||.
 Frog   159 YENVVVVSIQYRLGIMGFLSTGDKEVRGNFGFLDQVAALQWVRDNIKDFGGDPQSVTIFGESAGG 223

  Fly   206 ISVALHMLSPMSRGLFHRGICMSAAPYGP---VKYKDNDLQLAKRQAGLLKCPQESIGEMVECMR 267
            :||:..:|||:|.|||||.|..|.....|   ....:..|.|......:..|   |:.::|.|::
 Frog   224 LSVSALVLSPLSEGLFHRAIAESGVAILPGLTASKTEEILPLLDMVINVSSC---SVSDLVGCLK 285

  Fly   268 RKP------------YLDYVSTYNGMFEFGWNPVLNWRIVVEKDFGQERYLIESPFKTARRGDFH 320
            .|.            |:.:.:..:|:|    .|.....|:..|                   :.|
 Frog   286 NKTEDEIIEITAAMRYVIFPAVVDGVF----LPKPAEEILAAK-------------------ESH 327

  Fly   321 KVALITGITEFEFLSGAFFDLRNESIVNRYNRDWEHYASIALL--LEQNSTQSRAASRVFREKYM 383
            .|..:.||...||.|.....|.    :..|....|.....|:|  |...:|.|.....:. |:|.
 Frog   328 PVPFLIGINNHEFGSMLPVTLN----ITGYREGMEKKDIQAILGALPLLNTVSSVIPFIM-EEYF 387

  Fly   384 PESLDKLEYPKSLKG-----MGELL--SDALIGVSFHRFLQLMSPHTPIYTYLFRYK-GRYTFLK 440
            .::.|    ||.|:.     .|:::  ..||....:||     ....|:|.|.|::: ..|.
 Frog   388 GDTND----PKELRNNFLDLAGDIIFVIPALRTAKYHR-----DSGFPVYFYEFQHRPSLYA--- 440

  Fly   441 NPDNQQTIGPVHHDELIYLFHVGLLIPLLKR--------EDPENFMIELLTRMWIEFAQKGDPHN 497
              |:::......|.:.:|....|   |.||.        .:.|..:.:.:.:.|..||:.|||:.
 Frog   441 --DSKEDFVKADHGDELYFVGGG---PFLKNGILFKSNGTEEEKILSKTIMKYWANFARNGDPNG 500

  Fly   498 KNDEYLKGL-NWPLYNAQDKGYLEIGNNLTAKSG----GFFLNRYQIWEDLFP 545
                  .|| .||.|: :|:.||||  |||.||.    |   .|::.|....|
 Frog   501 ------HGLAEWPKYD-EDEDYLEI--NLTQKSSQRLKG---ERFEFWTITLP 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_001262469.1	COesterase	15..540	CDD:278561	175/566 (31%)
		Aes	40..>204	CDD:223730	77/179 (43%)
ces3.1	NP_001120019.1	COesterase	25..536	CDD:365897	175/566 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010