Protein Alignment CG4757 and nlgn1

DIOPT Version :9

• Sequence 1: NP_001262469.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: XP_017213657.1
• Gene: nlgn1 / 100002610
• ZFINID: ZDB-GENE-090918-1
• Length: 867
• Species: Danio rerio
• Alignment Length: 674
• Identity: 173/674 - (25%)
• Similarity: 264/674 - (39%)
• Gaps: 205/674 - (30%)

  Fly    13 LASSSVLSIEVD----TELGRVRG--ANLTSRLGVNFHAFRGIRYAEPPLGDLRFVNPQPVKPWS 71
            ||:|..|. |.|    |..|:|||  ..|.:.:......|.|:.||.||.|:.||..|:|...||
Zfish    43 LAASEKLD-ETDPIVTTTYGKVRGFKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPISWS 106

  Fly    72 PKIFDASEDGPMCPQP-------------W---------DNMTDVSEDCLRLNVY--TKDLK--- 109
             :|.:|::..|:|||.             |         ..:.|.|||||.||:|  |:|:|
Zfish   107 -EIRNATQFAPVCPQTLLEGRLPDVMLPVWFTNSIEVVSSYVQDQSEDCLFLNIYVPTEDVKRIS 170

  Fly   110 -------GR----------------------------------RPVIVFLHPGGFYVFSGQSKYL 133
                   |:                                  :||:||:|.|         .|:
Zfish   171 KECARKPGKKICRKGGPLSKKQNDDLADNDGAEDEDIRESGSPKPVMVFVHGG---------SYM 226

  Fly   134 AGPEHFMD-------RDCVLVSLNYRLGSLGFLATGSKEAPGNAGLKDQVLALRWIQQHIQRFGG 191
            .|..:..|       .:.:::::|||||.||||:||.:.|.||.||.|.:.||||..::|..|||
Zfish   227 EGTGNMFDGSILASYGNVIVITVNYRLGVLGFLSTGDQAAKGNYGLLDLIQALRWTSENIAFFGG 291

  Fly   192 DPDSVTLLGYSAGSISVALHMLSPMS---------RGLFHRGICMS-------AAPYGPVKYKDN 240
            ||..:|:.|..||:..|.|..||..|         :|||.|.|..|       |..:.|.||
Zfish   292 DPLRITVFGSGAGASCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQPAKY--- 353

  Fly   241 DLQLAKRQAGLLKCPQESIGEMVECMRRKPYLDYV--STYNGMFEFGWNPVLNWRIVVEKDFGQE 303
                |:..|..:.|..:...|||||:::|.|.:.|  ......:...:.||::..::.:    ..
Zfish   354 ----ARMLAKKVGCNLKDTVEMVECLQKKHYKELVEQDIQPARYHIAFGPVIDGDVIPD----DP 410

  Fly   304 RYLIESPFKTARRGDFHKVALITGITEFEFLSGAFFDLRNESIVNRYNRDWEHYASIALLLEQNS 368
            :.|:|       :|:|....::.|:.:.|.|......:.||:.|...:.|:
Zfish   411 QILME-------QGEFLNYDIMLGVNQGEGLKFVELIVDNENGVQANDFDY-------------- 454

  Fly   369 TQSRAASRVFREKY-MPESLDKLEYPKSLKGMGELLSDALIGVSFHR-------FLQLMSPH--- 422
                |.|....:.| .||..|.|.  :::|.|....:|.      |.       .|.|.:.|
Zfish   455 ----AVSSFVDDLYGYPEGKDILR--ETIKFMYTDWADR------HNPETRRKTLLALFTDHQWV 507

  Fly   423 --------------TPIYTYLFRYKGRYTFLKNPDNQQTIGPVHHDELIYLFHVGLLIPLLKRED 473
                          :|.|.|.|     |...:...........|.||:.|:|.:.::.|  ....
Zfish   508 APAVATADLHSSFGSPTYFYAF-----YHHCQTEQVPPWADAAHGDEIPYVFGLPMIGP--TELF 565

  Fly   474 PENF------MIELLTRMWIEFAQKGDP-----------HNKNDEYLKGLNWPLYNAQDKGYLEI 521
            |.||      :..::...|..||:.|||           |.|.:.: :.:.|..||.:|:.||.|
Zfish   566 PCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRF-EEVAWTRYNQKDQLYLHI 629

  Fly   522 GNNLTAKSGGFFLNRYQIWEDLFP 545
            |.....|. .:..|:..:|.:|.|
Zfish   630 GLKPRVKE-HYRANKVNLWLELVP 652

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_001262469.1	COesterase	15..540	CDD:278561	168/665 (25%)
		Aes	40..>204	CDD:223730	71/238 (30%)
nlgn1	XP_017213657.1	COesterase	53..647	CDD:306613	165/656 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575474
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740