Protein Alignment CG4757 and nlgn2b

DIOPT Version :9

• Sequence 1: NP_001262469.1
• Gene: CG4757 / 41330
• FlyBaseID: FBgn0027584
• Length: 550
• Species: Drosophila melanogaster
• Sequence 2: NP_001159808.1
• Gene: nlgn2b / 100002407
• ZFINID: ZDB-GENE-090918-3
• Length: 860
• Species: Danio rerio
• Alignment Length: 678
• Identity: 171/678 - (25%)
• Similarity: 278/678 - (41%)
• Gaps: 211/678 - (31%)

  Fly     3 MLFVVELLVLLASSSVLSIE--------VDTELGRVRGA--NLTSRLGVNFHAFRGIRYAEPPLG 57
            :::::.|.:.||.||....:        |.|..|::||.  .|.:.:......:.|:.||.||:|
Zfish    26 LVWLLGLALRLALSSCQRADLTTAKHPMVTTGYGKLRGVRKELNNEILGPVEQYLGVPYATPPVG 90

  Fly    58 DLRFVNPQPVKPWSPKIFDASEDGPMCPQ------------PW--DNM-------TDVSEDCLRL 101
            :.||..|:....|. :|.:|::..|:|||            .|  ||:       .:.|||||.|
Zfish    91 ERRFQPPEAPGSWQ-EIRNATQFAPVCPQNIHGVLPEIMLPVWFTDNLDAAAAYVQNQSEDCLYL 154

  Fly   102 NVYT---------------------KDLKGRR--PVIVFLHPGGFYVFSGQSKYLAGPEHFMDR- 142
            |||.                     :|::.||  ||::|:|.|.|         :.|..:..|.
Zfish   155 NVYVPTEDGPLTKKHDESSMNRPRDEDIRDRRKKPVMLFIHGGSF---------MEGTGNMFDAS 210

  Fly   143 ------DCVLVSLNYRLGSLGFLATGSKEAPGNAGLKDQVLALRWIQQHIQRFGGDPDSVTLLGY 201
                  :.::|::|||||.||||::|.:.|.||.||.||:.||||:.::|..|||||:.:|:.|.
Zfish   211 VLAAYGNVIVVTMNYRLGVLGFLSSGDQSAKGNYGLLDQIQALRWLNENIGHFGGDPERITIFGS 275

  Fly   202 SAGSISVALHMLSPMSRGLFHRGICMSAAP-------YGPVKYKDNDLQLAKRQAGLLKCPQESI 259
            .||:..|.|.:||..|.|||.|.|..|.:.       |.|:.|..   .|||:    :.|.....
Zfish   276 GAGASCVNLLILSHHSEGLFQRAIAQSGSAISSWSVNYRPLMYTK---ILAKK----VGCSYSDT 333

  Fly   260 GEMVECMRRKPYLDYV--STYNGMFEFGWNPVLNWRIVVEKDFGQERYLIESPFKTARRGDFHKV 322
            .::|:|:|||.|.:.|  ......:...:.||::..:|.           :.|....::|:|...
Zfish   334 ADLVDCLRRKSYRELVDQDVQPARYHIAFGPVVDGDVVP-----------DDPEILMQQGEFLNY 387

  Fly   323 ALITGITEFEFL------------SGAFFDLRNESIV-NRYNRDWEHYASIALLLEQNSTQSRAA 374
            .::.|:.:.|.|            |.|.||....:.| |.|.
Zfish   388 DILLGVNQGEGLKFVDDNEGEEGISAASFDYTISNFVDNLYG----------------------- 429

  Fly   375 SRVFREKYMPESLDKLEYPKSLKGM---------GELLSDALIGV-SFHRFLQLMSP-------- 421
                    .||..|.|.  :::|.|         |::....|:.: :.|   |.::|
Zfish   430 --------YPEGKDILR--ETIKFMYTDWADRDNGDMRRKTLLALFTDH---QWVAPAVATAKLH 481

  Fly   422 ---HTPIYTYLFRYKGRYTFLKNPDNQQTIGPVHHDELIYLFHVGLLIPLLKRED--PENF---- 477
               .:|:|.|.|.:     ..:.....:.....|.||:.|:|.|    |::...:  |.||
Zfish   482 AEFQSPVYFYTFHH-----HCQTEARPEWADAAHGDEIPYVFGV----PMVGATELFPCNFSKND 537

  Fly   478 --MIELLTRMWIEFAQKGDP-----------HNKNDEYLKGLNWPLYNAQDKGYLEIG------N 523
              :..::...|..||:.|||           |.|.:.: :.:.|..::::||.||.||      :
Zfish   538 IMLSAVVMTYWTNFAKTGDPNIPVPQDTKFIHTKPNRF-EEVIWTKFSSKDKQYLHIGLKPRIRD 601

  Fly   524 NLTAKSGGFFLNRYQIWEDLFP-LSSFH 550
            |..|       |:...|.:|.| |.:.|
Zfish   602 NYRA-------NKVAFWLELVPHLHTIH 622

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4757	NP_001262469.1	COesterase	15..540	CDD:278561	163/653 (25%)
		Aes	40..>204	CDD:223730	69/214 (32%)
nlgn2b	NP_001159808.1	COesterase	47..611	CDD:278561	161/644 (25%)
		Aes	<181..>279	CDD:223730	42/106 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575517
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740