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Protein Alignment mAcon2 and Aco2

DIOPT Version :9

Sequence 1:	NP_650042.2	Gene:	mAcon2 / 41326	FlyBaseID:	FBgn0037862	Length:	783	Species:	Drosophila melanogaster
Sequence 2:	NP_542364.1	Gene:	Aco2 / 11429	MGIID:	87880	Length:	780	Species:	Mus musculus

Alignment Length:	763	Identity:	537/763 - (70%)
Similarity:	622/763 - (81%)	Gaps:	4/763 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 VRNFHTARFPRCD--KVAMSNFDTGIPLPYKKLRENLDCIKGRLGGPLTLSEKVLYSHLDQPDSQ 78
            ||.:|.|.. .|.  |||||:|:....:.|..|.:|::.::.||..|||||||::|.|||.|.:|
Mouse    17 VRQYHVASV-LCQRAKVAMSHFEPSEYIRYDLLEKNINIVRKRLNRPLTLSEKIVYGHLDDPANQ 80

  Fly    79 EIERGKSYLRLRPDRVALQDATAQMTLLQFISSGLKKVAVPSTVHCDHLIEAQISGDKDLARAKD 143
            ||||||:||||||||||:|||||||.:||||||||.|||||||:|||||||||:.|:|||.||||
Mouse    81 EIERGKTYLRLRPDRVAMQDATAQMAMLQFISSGLPKVAVPSTIHCDHLIEAQVGGEKDLRRAKD 145

  Fly   144 LNKEVYDFLSSACAKYNLGFWKPGSGIIHQIILENYAFPGLLMIGTDSHTPNGGGLGCLCVGVGG 208
            :|:|||:||::|.|||.:|||:|||||||||||||||:||:|:||||||||||||||.:|:||||
Mouse   146 INQEVYNFLATAGAKYGVGFWRPGSGIIHQIILENYAYPGVLLIGTDSHTPNGGGLGGICIGVGG 210

  Fly   209 ADAVDVMANIPWELKCPTVIGCHLTGKISGWTSPKDVILKVAEILTVKGGTGAIVEYHGPGVESI 273
            ||||||||.||||||||.|||..|||.:||||||||||||||.|||||||||||||||||||:||
Mouse   211 ADAVDVMAGIPWELKCPKVIGVKLTGSLSGWTSPKDVILKVAGILTVKGGTGAIVEYHGPGVDSI 275

  Fly   274 SCTGMATITNMGAEIGATTSIFPFNERMVTYLRATGRGAIADEATKNKDLLVPDEGCKYDKVIEI 338
            ||||||||.|||||||||||:||:|.||..||..|||..||:.|.:.||.||||.||:||:||||
Mouse   276 SCTGMATICNMGAEIGATTSVFPYNHRMKKYLSKTGRTDIANLAEEFKDHLVPDPGCQYDQVIEI 340

  Fly   339 NLDTLEPLVNGPFTPDLAHPISKLGQNSEKNGYPMEIKVSLIGSCTNSSYEDMGRCASIANDALG 403
            ||:.|:|.:|||||||||||::.:|..:||.|:|::|:|.|||||||||||||||.|::|..||.
Mouse   341 NLNELKPHINGPFTPDLAHPVADVGTVAEKEGWPLDIRVGLIGSCTNSSYEDMGRSAAVAKQALA 405

  Fly   404 HGLKSCVPFNVTPGSEQVRATIARDGIIDVLEKFGGTVLANACGPCIGQWDRKDVKMGEKNTIVT 468
            ||||....|.:||||||:||||.|||...:|...||.|||||||||||||||||:|.||||||||
Mouse   406 HGLKCKSQFTITPGSEQIRATIERDGYAQILRDVGGIVLANACGPCIGQWDRKDIKKGEKNTIVT 470

  Fly   469 SYNRNFTGRNDANPATHCFVTSPEMATALAIAGRLDFNPMTDELTGTDGKTFKLKEPHGEELPSK 533
            ||||||||||||||.||.||||||:.|||||||.|.|||.||.|||.|||.|||:.|..:|||..
Mouse   471 SYNRNFTGRNDANPETHAFVTSPEIVTALAIAGTLKFNPETDFLTGKDGKKFKLEAPDADELPRS 535

  Fly   534 GFDPGEDTYQAPPAKADDIKVNVDPKSDRLQLLEPFEKWDGKDYIDLMVLIKIKGKCTTDHISAA 598
            .||||:||||.||..:...:|:|.|.|.||||||||:||||||..||.:|||:||||||||||||
Mouse   536 DFDPGQDTYQHPPKDSSGQRVDVSPTSQRLQLLEPFDKWDGKDLEDLQILIKVKGKCTTDHISAA 600

  Fly   599 GPWLKYRGHLDNISNNMFIGATNAENNEMNKVKNQKTGSFDAVPAVARDYKANKIKWCAVGEENY 663
            |||||:||||||||||:.|||.|.||.:.|.|:|..|..|..||..||.||.:.|:|..:|:|||
Mouse   601 GPWLKFRGHLDNISNNLLIGAINIENGKANSVRNAVTQEFGPVPDTARYYKKHGIRWVVIGDENY 665

  Fly   664 GEGSSREHAALEPRHLGGVAIIVKSFARIHETNLKKQGMLALTFANPGDYDKVQPSSKISILNLK 728
            ||||||||||||||||||.|||.|||||||||||||||:|.||||:|.||:|:.|..|::|..||
Mouse   666 GEGSSREHAALEPRHLGGRAIITKSFARIHETNLKKQGLLPLTFADPSDYNKIHPVDKLTIQGLK 730

  Fly   729 DLAPGKPVDAEIKN-NGSSDKIQLNHTLNELQIQWFQAGSALNLMKEL 775
            |.|||||:...||: ||:.:.|.||||.||.||:||:||||||.||||
Mouse   731 DFAPGKPLKCVIKHPNGTQETILLNHTFNETQIEWFRAGSALNRMKEL 778

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.