Protein Alignment Tengl4 and NUC1

DIOPT Version :10

• Sequence 1: NP_650038.2
• Gene: Tengl4 / 41321
• FlyBaseID: FBgn0037857
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_012327.1
• Gene: NUC1 / 853222
• SGDID: S000003744
• Length: 329
• Species: Saccharomyces cerevisiae
• Alignment Length: 297
• Identity: 79/297 - (26%)
• Similarity: 132/297 - (44%)
• Gaps: 52/297 - (17%)

  Fly   107 RKAHNAISKMTLSVGPNGSRHENIEHVADIMKYGFPGMDEIHVYKN---FVLSYDRRNRIAHWVC 168
            :|.::.|...:.:|.|:|           ..||||||  .||..:|   |:..|:|:.:..:||.
Yeast    41 QKPNSNIQSHSFNVDPSG-----------FFKYGFPG--PIHDLQNREEFISCYNRQTQNPYWVL 92

  Fly   169 EHVKSGCVQERDEKTLNKPNAYI-TDNTIPTIFSANMRDFKNSDWVGGHLASPQNYKCDALKFLE 232
            ||:....:..|:   .::.|::. .|..||..|...:||:..|.:..||.|...:.|.......:
Yeast    93 EHITPESLAARN---ADRKNSFFKEDEVIPEKFRGKLRDYFRSGYDRGHQAPAADAKFSQQAMDD 154

  Fly   233 AYKFTNIVP-INRGLKNHIWYRLESYVRDKAIEFDSVHVYTGPLFMPQRITFRN-WSVRYHVMG- 294
            .:..:|:.| :..|.....|..||.:.|....::.||.:.||||::|::....| :.|.|.|:|
Yeast   155 TFYLSNMCPQVGEGFNRDYWAHLEYFCRGLTKKYKSVRIVTGPLYLPKKDPIDNKFRVNYEVIGN 219

  Fly   295 MNTVAVPTHFFKIIIRE----DEFNRDMPIMEGYVVPNAYVDKDMDLRSFLADVRDIEHFAGLKF 355
            ..::||||||||:|:.|    :....|:.: ..:|:||..:..:..|..|...:..:|...||:.
Yeast   220 PPSIAVPTHFFKLIVAEAPTANPAREDIAV-AAFVLPNEPISNETKLTDFEVPIDALERSTGLEL 283

  Fly   356 CDGQQRDQLELPVKPPS--------------MTDFQN 378
                      |...|||              :.||.|
Yeast   284 ----------LQKVPPSKKKALCKEVNCQIVVRDFSN 310

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tengl4	NP_650038.2	Endonuclease_NS	132..362	CDD:460120	67/240 (28%)
NUC1	NP_012327.1	NUC	74..290	CDD:214683	60/229 (26%)