Protein Alignment Tengl4 and Endog

DIOPT Version :10

• Sequence 1: NP_650038.2
• Gene: Tengl4 / 41321
• FlyBaseID: FBgn0037857
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_031957.1
• Gene: Endog / 13804
• MGIID: 1261433
• Length: 294
• Species: Mus musculus
• Alignment Length: 280
• Identity: 85/280 - (30%)
• Similarity: 129/280 - (46%)
• Gaps: 48/280 - (17%)

  Fly    99 EHFLLWGRR--KAHNAISKM-----------TLSVGPNGSRHENIEHVADIMKYGFPGMDEIHVY 150
            ||   |.||  ||...:.::           .|..||.|.       ..::.|||.||:.::...
Mouse    21 EH---WRRREGKAPGLLGRVPLLPVVAADLPALPGGPAGG-------TGELAKYGLPGVAQLRSR 75

  Fly   151 KNFVLSYDRRNRIAHWVCEHV----------KSGCVQERDEKTLNKPNAYITDNTIPTIFSANMR 205
            :::|||||.|.|.|.||.|.:          :|.|             .:..|:::.....|...
Mouse    76 ESYVLSYDPRTRGALWVLEQLRPERLRGDGDRSAC-------------DFREDDSVHAYHRATNA 127

  Fly   206 DFKNSDWVGGHLASPQNYKCDALKFLEAYKFTNIVPINRGLKNHIWYRLESYVRDKAIEFDSVHV 270
            |::.|.:..||||:..|::.......:.:..:|:.|....|..:.|..||.|.|.....:.:|:|
Mouse   128 DYRGSGFDRGHLAAAANHRWSQRAMDDTFYLSNVAPQVPHLNQNAWNNLERYSRSLTRTYQNVYV 192

  Fly   271 YTGPLFMPQRITFRNWSVRYHVMGMNTVAVPTHFFKIIIREDEFNRDMPIMEGYVVPNAYVDKDM 335
            .|||||:|:........|:|.|:|.|.|||||||||::|.|....:..  :..||:|||.||:.:
Mouse   193 CTGPLFLPRTEADGKSYVKYQVIGKNHVAVPTHFFKVLILEAAGGQIE--LRSYVMPNAPVDETI 255

  Fly   336 DLRSFLADVRDIEHFAGLKF 355
            .|..||..:..||..:||.|
Mouse   256 PLERFLVPIESIERASGLLF 275

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tengl4	NP_650038.2	Endonuclease_NS	132..362	CDD:460120	74/234 (32%)
Endog	NP_031957.1	NUC	75..281	CDD:214683	69/216 (32%)
		Essential for deoxyribonuclease activity. /evidence=ECO:0000269|PubMed:32192768	283..293