DRSC/TRiP Functional Genomics Resources

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Protein Alignment Leash and si:dkey-172m14.1

DIOPT Version :9

Sequence 1:NP_650037.2 Gene:Leash / 41320 FlyBaseID:FBgn0037856 Length:520 Species:Drosophila melanogaster
Sequence 2:NP_001188367.2 Gene:si:dkey-172m14.1 / 567451 ZFINID:ZDB-GENE-060526-221 Length:399 Species:Danio rerio


Alignment Length:527 Identity:113/527 - (21%)
Similarity:180/527 - (34%) Gaps:183/527 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly    20 GDIIRGEIWMNVNKRTKIRAIKVQVTGKGKCKWME----ILRKNSNNNEYSRSLFY----TSKEV 76
            |||:.|.:.:.|.|...:..:.|::||....:|.|    ..|..|::..|.:...|    :||:.
Zfish    24 GDIVEGRVVLEVTKEINVENLFVKLTGDADVRWTEGSGDDERSYSDHERYFKQKQYFIQDSSKKG 88

  Fly    77 YEHSETPLPDFEPRGLELSAGEHTFIFEVALGRQ-LPSSFKGSYGAIKYKMRVLIQRPW--TFDE 138
            .....|.|...|..|..:..|.|.|.|...|.:| :|.:|||.:|.:||.:.|.::|.|  |...
Zfish    89 QCEKNTTLVSGETYGSVIKPGSHVFPFRFQLPQQNMPPTFKGFHGWVKYIVMVKLKRSWKPTSSA 153

  Fly   139 RHTIPFTV----VKNMPLQPMQRSIPSSLEKQVTKTISLFGTRPITLLALLPEDFAVRGEPLRIC 199
            :..|.|..    ..:..|||.     |..|   .|.:.|||:..:::.....:...:.||.:|:.
Zfish   154 QAEINFAPRNFGTNDHLLQPQ-----SGTE---DKKMKLFGSGKMSMTVTTDKTGYMLGEIIRVS 210

  Fly   200 ATVINNSTTAVEKLRFTVLQYVTY-------YSHVPLRVQKVECIAVATKETGSVQKKTERSFAH 257
            ..:.|:|:..: ||::::.|..|:       ::|..:..:..:||....|          ..|..
Zfish   211 VDIDNSSSRDI-KLKYSLKQLQTFIAGRSTTHAHKDIVKETKDCIPSGGK----------TRFVV 264

  Fly   258 ELLLPDGAQPTDEQMSGVITIVYELRVEAVLRGFFKNLILNLPFKVYSQDPSNRQSSLRPPP--- 319
            ::.||.....|.|... :|.:.|||:|           .|::.|   :.||:.:...:..||   
Zfish   265 DIKLPHDIMVTIENCR-IIKVQYELKV-----------YLDVSF---ASDPTVKFPVVIIPPLQQ 314

  Fly   320 -PPRPNDGPPGPELGSGNLFEPALPVYPSLDSSIGSPSHSSQFSECSSINSITSDSSAATLSPAV 383
             ||. :|.||                                                       
Zfish   315 CPPW-HDPPP------------------------------------------------------- 323

  Fly   384 GAGTGGMDMSYTSGSQSSQYGSPSARTSLRSSNVPYMPYSSSPLMVQSYPPPHLPAYPPPESPQY 448
                                              ||||           |.|:|..||.      
Zfish   324 ----------------------------------PYMP-----------PQPNLVPYPG------ 337

  Fly   449 SLLALTPPPAGVV-----AAPPTGGAAAGGAPAYSQLPSTSASASFLQPRQAPGAHELPPSYEEL 508
               ...|||||:.     ..||..|.|||      ..|:.:|......|..:...::|..|.:|.
Zfish   338 ---GAAPPPAGLYPNLYDPVPPYPGTAAG------TFPNPNAMLPGFHPAPSAPVYDLNQSTKES 393

  Fly   509 FGLANAP 515
            |  .|||
Zfish   394 F--PNAP 398

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LeashNP_650037.2 Arrestin_N 6..152 CDD:304627 40/146 (27%)
Arrestin_C 178..305 CDD:280848 25/133 (19%)
si:dkey-172m14.1NP_001188367.2 Arrestin_N 24..149 CDD:304627 37/124 (30%)
Arrestin_C 187..308 CDD:280848 27/146 (18%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D311636at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
11.010

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