Protein Alignment Leash and CG2993

DIOPT Version :10

• Sequence 1: NP_650037.2
• Gene: Leash / 41320
• FlyBaseID: FBgn0037856
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_001262348.1
• Gene: CG2993 / 40924
• FlyBaseID: FBgn0037521
• Length: 545
• Species: Drosophila melanogaster
• Alignment Length: 470
• Identity: 106/470 - (22%)
• Similarity: 186/470 - (39%)
• Gaps: 84/470 - (17%)

  Fly    16 VYFAGDIIRGEIWMNVNKRTKIRAIKVQVTGKGKCKWMEILRKNSNNNEYSRSL-----FYTSKE 75
            ||:||..:.|.:.::|:...:|:.|.|.|:|..|.:|:    |.....:..|::     .|.|..
  Fly    16 VYYAGQELSGVVDLSVDATKRIKGIHVTVSGYAKIRWI----KKGYPRDSERAMCRAYRSYLSSR 76

  Fly    76 VY------EHSETPLPDFEPRGLELSAGEHTFIFEVALGRQLPSSFKGSYGAIKYKMRVLIQRPW 134
            .|      .:|....|          |||:::.|.|.|...||:||.|.||.|.|::...|:|..
  Fly    77 SYVLGSCANNSSIDWP----------AGEYSYTFHVILPDNLPTSFDGKYGQIHYEIITTIERAA 131

  Fly   135 TFDERHTIPFTVVK----------NMPLQPMQRSIPSSLEKQVTKTISLF--GTRPITLLALLPE 187
            ...:...:||||::          .:||:.:.|           |....|  .|.|:|:....|.
  Fly   132 RHPKVFKLPFTVIQPLDLNADAIYRVPLEILDR-----------KRFWSFCCPTGPLTVKFSTPY 185

  Fly   188 DFAVRGEPLRICATVINNSTTAVEKLRFTVLQYVTYYSHVPLRVQKVECIAVATKETGSVQKKTE 252
            .....|:.:.....:.|.|:..:.:....:.|.|:|.||.|....:.:...:|.|:.|:|.:.:.
  Fly   186 CGYAPGQKIHFVLYINNESSIDIIECEVKLKQEVSYESHDPQHEYRYDKHLIARKQFGNVLRWSR 250

  Fly   253 RSFAHELLLPDGAQPTDEQMSGVITIVYELRVEAVLRGFFKNLILNLPFKVYS----QDPS---- 309
            :.:...|.|| ...||..:.:..|::.|.:::......|...|.|.:|..:.|    ..|.
  Fly   251 KVYRGYLDLP-SIPPTSVKPTCPISVNYSIKIIVNPTEFHWKLKLKIPLTIGSIPIMDGPEALLR 314

  Fly   310 -NRQ--------SSLRPPPPPRPNDGPPGPELGSGNLFEPALPVYPSLDSSIGSPSHSSQFSECS 365
             |||        .:|:.....|..|.....::.        :......|......|.|.|....|
  Fly   315 FNRQQQQHQVVSQNLQMSTQQRQRDRDRDRDMN--------VDRERDRDRDRDRISASVQQRRIS 371

  Fly   366 SINSITSDSSAATLSPAVGAGTGGMDMSYTSGSQSSQYGSPSA---RTSLRSSNVPYMPYSSSPL 427
            |||:  ::::...|...:......|:| .|:.|.:....:||:   ..:||.:.:|.:..:|.
  Fly   372 SINN--NNNNHGRLVGGLLPTNSNMNM-ITNVSPTPTSSTPSSTPTTAALRPTAMPAILVTSD-- 431

  Fly   428 MVQSYPPPHLPAYPP 442
              ...||.::|..||
  Fly   432 --SDNPPDYIPMMPP 444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Leash	NP_650037.2	Arrestin_N	6..152	CDD:451447	41/156 (26%)
		Arrestin_C	191..308	CDD:214976	25/120 (21%)
CG2993	NP_001262348.1	Arrestin_N	5..150	CDD:451447	41/147 (28%)
		Arrestin_C	174..304	CDD:214976	29/130 (22%)