DRSC/TRiP Functional Genomics Resources

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Protein Alignment Leash and txnipa

DIOPT Version :10

Sequence 1:NP_650037.2 Gene:Leash / 41320 FlyBaseID:FBgn0037856 Length:520 Species:Drosophila melanogaster
Sequence 2:NP_956381.1 Gene:txnipa / 368359 ZFINID:ZDB-GENE-030804-10 Length:400 Species:Danio rerio


Alignment Length:417 Identity:91/417 - (21%)
Similarity:151/417 - (36%) Gaps:114/417 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    11 DSADRVYFAGDIIRGEIWMNVNKRTKIRAIKV---------QVTGKGKC-------KWMEILRKN 59
            |.:...|.:||.:.|::.:.|::.|::.|:||         ...||.:|       |:.::::.:
Zfish    17 DPSKTFYCSGDKVAGKVLVEVSEVTRVMAMKVLGVGCAKVEYAKGKQRCREEVDYLKYEDVVQLD 81

  Fly    60 SNNNEYSRSLFYTSKEVYEHSETPLPDFEPRGLELSAGEHTFIFEVALGRQLPSSFKGSYGAIKY 124
            .:..:...|:.......||:|                    |.||:....||.||:||.:|.::|
Zfish    82 EHPTDNDGSVILRPGNKYEYS--------------------FGFELPAQGQLVSSYKGKFGFVQY 126

  Fly   125 KMRVLIQRPW---TFDERHTIPFTVVKNMPLQPMQRSIPSSL-------EKQVTKTISLFGTRPI 179
            .::.|::||.   ...::|   |.|.     :|:..:.|..|       ||:||......|  .:
Zfish   127 YVKALMERPCQPALECKKH---FEVE-----EPLDVNTPDLLSPTGGMKEKKVTCMFIPDG--QV 181

  Fly   180 TLLALLPEDFAVRGEPLRICATVINN-STTAVEKLRFTVLQYVTYYSHVPLRV--QKVECIAVAT 241
            :|.|.:.......||.:.|.|...|. |...|.|......|  ||.::...:|  ||:..:....
Zfish   182 SLNAKIDRRGFCEGEEICIDAKFENTCSRIVVPKAAIVAKQ--TYQANGRTKVFRQKLSSVRGNH 244

  Fly   242 KETGSVQKKTERSFAHELLLPD--GAQPTDEQMSGVITIVYELRVEAVLRGFFKNLILNLPF--- 301
            ..:|.......:|.....:.|.  |.        .:|.:.|.|.:...:.|..| |||.||.   
Zfish   245 IISGMCDAWQGKSIRVPKIKPSILGC--------NIIRVEYALMIYMHIPGSEK-LILELPLVIG 300

  Fly   302 ------------KVYSQD-----PSNRQSSLRPPPPPRPN---------------------DGPP 328
                        .:.|||     .||...|||.|....|:                     ||..
Zfish   301 TVPYNGFGSRTNSMSSQDGSISNASNSWVSLRMPSSAPPSYCDITRDCCIDQPLTPLLDDYDGGD 365

  Fly   329 GPELGSGNLFE-PALPVYPSLDSSIGS 354
            .|...:...|: |.||.|..::....:
Zfish   366 SPIFMNAAQFQFPPLPAYSEVEEEFNA 392

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LeashNP_650037.2 Arrestin_N 6..152 CDD:451447 35/159 (22%)
Arrestin_C 191..308 CDD:214976 31/141 (22%)
txnipaNP_956381.1 Arrestin_N 11..155 CDD:451447 36/165 (22%)
Arrestin_C 178..304 CDD:214976 31/138 (22%)

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