Protein Alignment Leash and arrdc2

DIOPT Version :10

• Sequence 1: NP_650037.2
• Gene: Leash / 41320
• FlyBaseID: FBgn0037856
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_956233.1
• Gene: arrdc2 / 335206
• ZFINID: ZDB-GENE-030131-7146
• Length: 407
• Species: Danio rerio
• Alignment Length: 418
• Identity: 95/418 - (22%)
• Similarity: 163/418 - (38%)
• Gaps: 104/418 - (24%)

  Fly     4 ERLRITLDSADR----VYFAGDIIRGEIWMNVNKRTKIRAIKVQVTGKGKCKWMEILRKNSN--- 61
            ::..|..||.:.    ||.:||::.|::.:..:..:||.::|:...|..|..|.|.....|:
Zfish     7 KKFDIVFDSPEMDCPPVYSSGDVVSGKVVLEFSAESKIDSLKLHAEGFAKVHWTESRSAGSSTAY 71

  Fly    62 NNEYSRSLFYTS-KEVYEHSE----TPLPDFEPRGLELSAGEHTFIFEVALGRQ-LPSSFKGSYG 120
            ...||..:.|.: :||...::    |.:|          ||.|.:.|...|..: |.:||:|.:|
Zfish    72 TQNYSDEVEYLNRREVLLQADNGDLTVIP----------AGRHEYPFSFQLPEETLVTSFEGKHG 126

  Fly   121 AIKYKMRVLIQRPWTFDERHTIPFTVVKNMPLQPMQRSIPSSLEKQVTKTISLFGTR-------- 177
            :|:|.::|.:.|||...::....|||:     :|:..:.||.|..|.       ||:
Zfish   127 SIRYWVKVKLHRPWATVKKIKKEFTVI-----EPIDINTPSLLAPQA-------GTKDKMARIWY 179

  Fly   178 ----PITLLALLPEDFAVRGEPLRICATVINNSTTAVEKLRFTVLQYVTYYSHVPLRVQKVECIA 238
                .:::.|.:.......||.:.:.|...|:::.:|....: :.|..|:.:...::.::    |
Zfish   180 RNCGQVSITAKIDRKGYTPGEVIPVFAEFDNSTSRSVVPKAY-ITQTQTFIARGTMKQKR----A 239

  Fly   239 VATKETGSVQKKTERSFAHELLL---PDGAQPTDEQMSGVITIVYELRVEAVLRGFFKNLILNLP 300
            |.....|.:.....|...|...:   |.|  |:..|.. :|.:.|.|||...:.|..| |.|.||
Zfish   240 VVATLCGDIVGPRRRETWHGRAIKIPPVG--PSILQCR-IIKVEYMLRVCVDVPGTSK-LSLELP 300

  Fly   301 FKVYSQDP----SNRQSSL-----------------RPPPPP-----------RPNDGPPGPELG 333
            . |....|    .:|.||:                 :|.|||           ..|.....||..
Zfish   301 L-VMGTIPLHPFGSRTSSVSSQYSVNMEWLRMAIPEQPEPPPDYSSVVTEEEAAQNSTAVQPEED 364

  Fly   334 SGNLFEPAL------------PVYPSLD 349
            ...|.:.:|            |||..:|
Zfish   365 LSGLLQHSLIAYMQEFRSRPPPVYSEVD 392

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Leash	NP_650037.2	Arrestin_N	6..152	CDD:451447	42/158 (27%)
		Arrestin_C	191..308	CDD:214976	28/119 (24%)
arrdc2	NP_956233.1	Arrestin_N	9..159	CDD:425619	43/164 (26%)
		Arrestin_C	183..308	CDD:214976	29/134 (22%)