Protein Alignment Leash and aly1

DIOPT Version :10

• Sequence 1: NP_650037.2
• Gene: Leash / 41320
• FlyBaseID: FBgn0037856
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_595242.2
• Gene: aly1 / 2541205
• PomBaseID: SPBC839.02
• Length: 504
• Species: Schizosaccharomyces pombe
• Alignment Length: 484
• Identity: 94/484 - (19%)
• Similarity: 166/484 - (34%)
• Gaps: 166/484 - (34%)

  Fly    22 IIRGEIWMNVNKRTKIRAIKVQVTGKGKCKWME--------ILRKNSNNNEYSRSLFYTSKEVYE 78
            ::||.:.:.:.|..|::.|::...||.:.:|.|        ...:||..| :....|::.::|.|
pombe    98 VLRGSLCIQIYKPVKLKKIQLSFKGKSRTEWPEGIPPKLFDTYEENSIMN-HCWVFFHSEQKVDE 161

  Fly    79 HSE-----TPLPDFE-----PRGLE-LSAGEHTFIFEVALGRQLPSSFKGSYGAIKYKMRVLIQR 132
            :|.     ..||.:.     ||.:| ...||:.:.||:.:....|.|.:...|.:.|.:..|:.|
pombe   162 NSHGAVWYKVLPHYADTAHYPRSMECFYPGEYVYNFELPISCTYPESIQTDMGRVYYFLETLVDR 226

  Fly   133 PWTFDERHT--IPFTVVKNMPLQPMQRSIPSSLEKQVTKTIS-------LFGTRPITLLALLPED 188
            ..||..:.|  ||..::::    |...|:.:|....|:|:..       ..|.:.:.:..::|.:
pombe   227 SSTFSGKSTGRIPIELIRS----PCSTSVATSEPILVSKSWEDRLHYEVQVGEKCVVMGQVVPVN 287

  Fly   189 --FAVRGEPLRICATVINNSTTAVEKLRFTVLQYVTYYSHVPLRVQKVECIAVATKETGSVQKKT 251
              |.:.||             ....|||..:::...||           |      ...||::|.
pombe   288 FKFTLLGE-------------VKFHKLRLFLMERRYYY-----------C------RQRSVRRKE 322

  Fly   252 ERSFAHELLLPDGAQPTDE----QMSGVITIVYELRVEAVLRG-------------FFKNLIL-- 297
            :   ..:|||.:.:.|.::    ....|...||||..:..:.|             .:.|:.:
pombe   323 K---TRQLLLYERSAPKNQCLLSDWKQVRPDVYELSDQVRIPGCHDMAANIVHFDTTYPNIKITH 384

  Fly   298 -----------NLP--------FKVYSQDPSNRQSSLRPPPPPRPNDGPPGPELGSGNLFEPALP 343
                       |.|        .::|...|....|.       |.:||        ..:.....|
pombe   385 TVRTVLRFSCENSPELMGSAKYLEIYIDSPVRLLSC-------RCSDG--------STMLPAYCP 434

  Fly   344 VYPSLDSSIGSPSHSSQFSECSSINSITS--DSSAATLSPAVGAGTGGMDMSYTSGSQSSQYGSP 406
            :.|           ||:.:.||..|.|.:  :...|..|..:|......| |:|:
pombe   435 IIP-----------SSEVNFCSIDNRIIAGMNRDLALDSDIIGNSPPSFD-SWTA---------- 477

  Fly   407 SARTSLRSSNVPYMPYSSSPLMVQSYPPP 435
                      |||..           |||
pombe   478 ----------VPYQA-----------PPP 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Leash	NP_650037.2	Arrestin_N	6..152	CDD:451447	36/150 (24%)
		Arrestin_C	191..308	CDD:214976	25/154 (16%)
aly1	NP_595242.2	Arrestin_N	101..227	CDD:451447	29/126 (23%)
		Arrestin_C	263..422	CDD:214976	30/198 (15%)