Protein Alignment Leash and arrd-16

DIOPT Version :10

• Sequence 1: NP_650037.2
• Gene: Leash / 41320
• FlyBaseID: FBgn0037856
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_499629.2
• Gene: arrd-16 / 190071
• WormBaseID: WBGene00013043
• Length: 399
• Species: Caenorhabditis elegans
• Alignment Length: 317
• Identity: 68/317 - (21%)
• Similarity: 137/317 - (43%)
• Gaps: 35/317 - (11%)

  Fly     6 LRITLDSADRVYFAGDIIRGEIWMNVNKRTKIRAIKVQVTGKGKCKWMEILRKNSNNNEYSRSLF 70
            |.:.|.:.:::|..|..|.|.:..::.:..|::||::...|....||: :...:.:::..||.:.
 Worm     5 LALGLSNCEQIYEPGGTIEGYVTFDLRESVKVKAIRISAEGLATTKWL-LSESSKSSHGRSREVS 68

  Fly    71 YTSKEVYEHSETPLPDFEP-RGLELSA---GEHTFIFEVALGRQLPSSFKGSYGAIKYKMRVLIQ 131
            |::|..|...|..:  ::| .|...|:   |.|.:.|:..:...:|.||:|.:|.|:|.|:..::
 Worm    69 YSAKVTYLDEEQMV--WKPSEGHSKSSVFPGIHVYPFKFQIPIGVPPSFEGDHGNIRYHMKATVE 131

  Fly   132 RPWTFDERHTIPFTVVKNMPLQPMQRSIPSSLEKQVTKT----ISLFGTRPITLLALLPEDFAVR 192
            |||..:...|...|:   :|.:.:.:.:.:|.|....|:    ..||....:.|...:|:...|.
 Worm   132 RPWKTNRSVTRYLTI---LPPKDLNKEVLASEETSSWKSKKVGFFLFRYGKVNLQIRIPKKGYVP 193

  Fly   193 GEPLRICATVINNSTTAVEKLRFTVLQ---YVTYYSHVP-----------------LRVQKVECI 237
            ||.:.|...:.|.|:..:.|....::|   ::.|...:.                 |..::.|..
 Worm   194 GETISIETNIDNMSSRPILKTECYLIQQCRFLAYRYGISGPTDGRRASSLSENDRYLSRKRDEIK 258

  Fly   238 AVATKETGSVQKKTERSFAHELLLPDGAQPTDEQMSGV-ITIVYELRVEAVLRGFFK 293
            .|:......::.:||......|.:|......|..:..| ..:|.:|.|:..:|...|
 Worm   259 IVSVIHEMHIEPRTEHKAKMRLKIPCTCPTFDSTLIHVEYFVVVKLHVKCRMRNTVK 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Leash	NP_650037.2	Arrestin_N	6..152	CDD:451447	37/149 (25%)
		Arrestin_C	191..308	CDD:214976	23/124 (19%)
arrd-16	NP_499629.2	Arrestin_N	9..153	CDD:425619	37/149 (25%)
		Arrestin_C	178..327	CDD:214976	25/138 (18%)