DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Leash and arrd-12

DIOPT Version :9

Sequence 1:	NP_650037.2	Gene:	Leash / 41320	FlyBaseID:	FBgn0037856	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_001309576.1	Gene:	arrd-12 / 187636	WormBaseID:	WBGene00011053	Length:	186	Species:	Caenorhabditis elegans

Alignment Length:	156	Identity:	41/156 - (26%)
Similarity:	68/156 - (43%)	Gaps:	11/156 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 ITLDSADRVYFAGDIIRGEIWMNVNKRTKIRAIKVQVTGKGKCKW--MEILRKNSNNNE---YSR 67
            :..|..:.||.||..|.|.:..:...:...|.|.||:.|:....:  .|...|.::..|   .:.
Worm     6 VLFDKPNAVYAAGQKISGRVVFSTASQQNPRWIDVQLHGRSHTFFTRQESETKTNSKGESETKTH 70

  Fly    68 SLFYTSKEVYEHSETPLPDFEPRGLELSAGEHTFIFEVALG-RQLPSSFKGSYGAIKYKMRVLIQ 131
            ::.||:...:..:..||.....:...|..|::.:.|...|. ..||.||:|:.|.|:|.:|..:.
Worm    71 TVHYTATAKHLDTAVPLWRKTDKAARLLPGKYEWQFWFQLPCSVLPPSFEGNNGNIRYWVRAEVS 135

  Fly   132 RPWTF---DER--HTIPFTVVKNMPL 152
            |.|.|   ||.  ...||..:..||:
Worm   136 RSWKFNIVDESSFEIAPFLDLNTMPI 161

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Leash	NP_650037.2	Arrestin_N	6..152	CDD:304627	40/154 (26%)
Leash	NP_650037.2	Arrestin_C	178..305	CDD:280848
arrd-12	NP_001309576.1	Arrestin_N	6..157	CDD:389964	39/150 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3780
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D311636at33208
OrthoFinder	1	1.000	-	-		FOG0000089
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820