Protein Alignment Leash and arrd-6

DIOPT Version :9

• Sequence 1: NP_650037.2
• Gene: Leash / 41320
• FlyBaseID: FBgn0037856
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_001254290.1
• Gene: arrd-6 / 185541
• WormBaseID: WBGene00009579
• Length: 469
• Species: Caenorhabditis elegans
• Alignment Length: 471
• Identity: 109/471 - (23%)
• Similarity: 179/471 - (38%)
• Gaps: 110/471 - (23%)

  Fly     6 LRITLDSADRVYFAGDIIRGEIWMNVNKRTKIRAIKVQVTGKGKCKWMEIL----RKNSNNNEY- 65
            :|:..|    ||:||:.|.|.:.:...:..|||.|:|.:.||.... ::::    |:...:::|
 Worm    36 IRLNKD----VYYAGETISGSVLLENTENIKIRGIRVLLRGKVHAT-LKVVKSGERRTLKDDQYV 95

  Fly    66 --SRSLFYTSKEVYEHSETPLPDFEPRGLELSAGEHTFIFEVALGR-QLPSSFKGSYGAIKYKMR 127
              .:.|.:...:..|....|:         |:.|.|.|.|...|.: .||.|.:..:..|:|..:
 Worm    96 LDEKQLLWGKDKSDESDSVPI---------LARGVHQFSFNFDLPQSSLPCSLESRHCTIRYYFK 151

  Fly   128 VLIQRPWTFDERHTIPFTVVKNMPLQPMQRSIPSSLEKQVTKTISLFGTR--PITLLALLPEDFA 190
            |:|..|:....:....||:: ...:..|:....|.|..|..|....:..:  .:.|..:|.....
 Worm   152 VIIDIPYASSPQGIKYFTII-GPHIDSMEEKYLSPLSAQDRKVNCCWCCQRGALALRIILERTAY 215

  Fly   191 VRGEPLRICATVINNSTTAVEKLRFTVLQYVTYYSHVPLRVQK--------VECIAVATKE---T 244
            |.||.:|:.|.:.|..:|| :.|...::|      ||.:.|:|        :.|:....|.   .
 Worm   216 VCGENIRVRAQIENRQSTA-QSLVIRLVQ------HVEVFVEKGLLGENKMMSCVVFEHKSPAIA 273

  Fly   245 GSVQKKTERSFAHELLLPDGAQPTDEQMSGVITIVYELRV-------EAVLRGFFKNLILNLPFK 302
            .:.|.|.:.:....:.|| ...||...:..:|.|.|.|||       ...|...|...:..:|::
 Worm   274 ANSQGKYDSTLEQPIRLP-VVPPTLVGVCRLIQIYYALRVCMEDEKGNECLHIDFPLTVATIPYR 337

  Fly   303 VYSQDPSNRQSSLRPPPPPRPND--------GP-PGPELGSGNLFEPA-------------LPVY 345
            :    |:       .||||...|        |. ..||...|.:::..             .|||
 Worm   338 I----PN-------APPPPVDYDFCSNHVEGGKYVSPEFRLGQVYDGEGEEINKEEEIVLYRPVY 391

  Fly   346 PSL-DSSIGSPSHSSQFSECSSINSIT--SDSSAATL---------------SPAVGAGTGGMD- 391
            ..| |..||||..|..|..    .|.|  :|||.|.:               :|.:......||
 Worm   392 VKLADRRIGSPHVSKDFRS----GSFTRIADSSLALVTEPNGSRRRSILVASNPCLAMRDESMDE 452

  Fly   392 -MSYTSGSQSSQYGSP 406
             :..|:|..|.  |.|
 Worm   453 KLMMTNGCNSE--GDP 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Leash	NP_650037.2	Arrestin_N	6..152	CDD:304627	36/153 (24%)
		Arrestin_C	178..305	CDD:280848	33/144 (23%)
arrd-6	NP_001254290.1	Arrestin_N	34..174	CDD:278754	36/152 (24%)
		Arrestin_C	201..336	CDD:214976	32/142 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D311636at33208
OrthoFinder	1	1.000	-	-		FOG0000089
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920