Protein Alignment Leash and arrd-25

DIOPT Version :9

• Sequence 1: NP_650037.2
• Gene: Leash / 41320
• FlyBaseID: FBgn0037856
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_510338.1
• Gene: arrd-25 / 181514
• WormBaseID: WBGene00007296
• Length: 584
• Species: Caenorhabditis elegans
• Alignment Length: 427
• Identity: 100/427 - (23%)
• Similarity: 178/427 - (41%)
• Gaps: 91/427 - (21%)

  Fly     5 RLRITLDSADRVYF-AGDIIRGEIWMNVNKRTKIRAIKVQVTGKGKCKWM-EILRKNSNNNEYSR 67
            |..|.||:.|...| .|::|.|::.:.:.|...|.|:|:|:  ||:..|: :.|:|:.....|
 Worm    10 RFDIHLDAGDEPTFKGGELITGKLLIELRKPIIINAVKLQM--KGRAAWLNDPLKKDDIEKVY-- 70

  Fly    68 SLFYTSKEVYEHSETPLPDFEPRGLELSAGEHTFI--FEVALGRQLPSSFKGSYGAIKYKMRVLI 130
                 ..:.:...|.|....||...:. .|:.|:.  ||..|.:..||:::|.:..|:|.:|..:
 Worm    71 -----FDQDFTLLERPPGKPEPGHFQW-IGDFTYSLPFECPLPKGCPSTYEGPHAFIRYFIRASL 129

  Fly   131 QRPWTFDERHTI----PFTVVKNMPLQPMQRSIPSSLEKQVTKTISLFG-----TRPITLLAL-- 184
            .:...|::.|..    .||:|     .|.:..|.:. |...|...::.|     ::....|||
 Worm   130 VQEDEFEKIHEYYVKKAFTLV-----SPSEGHIVTG-EAAQTDDSAILGKCCCKSKLAAELALSK 188

  Fly   185 ---LPEDFAVRGEPLRICA----TVINN-STTAVEKLRFTVLQYVTYYSHVPLR---VQKVECIA 238
               ||.: |:.|. |:|.:    .::|: ....|:::|......::..|  |.|   |:|:|
 Worm   189 TGYLPGE-AIYGN-LKIGSKHPKDILNHMEARLVDRVRRVGAPEISAAS--PWRTLLVRKLE--- 246

  Fly   239 VATKETGSVQK-KTERSFAHELLLPDGAQPTD---EQMSGVITIV--YELRVE----AVLR---- 289
             :.:||.:..| ..|:|....|.:|.....|.   |..|.:..|:  |...:|    |.||
 Worm   247 -SNQETPAKTKGAIEQSGLFLLTVPPVCPSTKGDYEDPSKIEHILSPYGKLLESPSTATLRFRKI 310

  Fly   290 GFFK-----------NLILNLPFKV---YSQDPSNRQSSLRPPPPPRPNDGPPGPELGSGNLFEP 340
            .|.|           :::|.:|.::   .::|.||...|....|.|.......|....:|    |
 Worm   311 PFLKVEYGIQVTLGTDILLEIPIEIGELSTRDKSNTLESFVTGPQPVEEADEKGKIAVNG----P 371

  Fly   341 AL--PVYPSLDSSIGSPSHSSQFSECSSINSITSDSS 375
            .:  ||||       .|.::....:.:|:..|:::.|
 Worm   372 FVYTPVYP-------YPQNAGTNGKAASVTVISTEPS 401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Leash	NP_650037.2	Arrestin_N	6..152	CDD:304627	39/153 (25%)
		Arrestin_C	178..305	CDD:280848	38/167 (23%)
arrd-25	NP_510338.1	Arrestin_N	11..152	CDD:389964	39/155 (25%)
		Arrestin_C	179..336	CDD:214976	38/164 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3780
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D311636at33208
OrthoFinder	1	1.000	-	-		FOG0000089
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11188
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920