Protein Alignment Leash and arrd-2

DIOPT Version :9

• Sequence 1: NP_650037.2
• Gene: Leash / 41320
• FlyBaseID: FBgn0037856
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_496008.1
• Gene: arrd-2 / 174491
• WormBaseID: WBGene00013086
• Length: 334
• Species: Caenorhabditis elegans
• Alignment Length: 364
• Identity: 87/364 - (23%)
• Similarity: 135/364 - (37%)
• Gaps: 83/364 - (22%)

  Fly     6 LRITLDSADRVYFAGDIIRGEIWMNVNKRTKIRAIKVQVTGKGKCKWMEILRKNSNNNEYSRSLF 70
            :.|...:..:.|..||.:.|::.:........|.:::...|:.||        |...:|
 Worm     3 VNIVFSNPSKTYLPGDYVSGKVLLTTKDPISARYMEITWKGESKC--------NFGGSE------ 53

  Fly    71 YTSKEVYEH-SETPLPDFEPRGLE-LSAGEHTFIFEVALGRQLPSSFKGSYGAIKYKMRVLIQRP 133
              |..|..| :.|.:......|:: :.||.....|...|....|.||.|.:|.|:|.:.|...||
 Worm    54 --SSNVQRHLAGTFMGWIAKDGVDTIPAGTLKSRFRFRLPENSPPSFCGMFGEIEYSVTVEFDRP 116

  Fly   134 WTFDERHTIPFTVVK--NMPL-QPMQRSIPSSLEKQVTKTISLFGTRPITLLALLPEDFAVR--- 192
            |....:....|.||:  |:.| :|........::.:.:.||...|      |.||...|:.|
 Worm   117 WRLKLKMMNTFRVVQKTNLTLSEPKMMKYAEFVKSKNSGTIFKDG------LFLLKLHFSKRAFL 175

  Fly   193 -GEPLRICATVINNSTTAVEKLRFTVLQYVTYYSHVPLRVQKVECIAVATKETGSVQKKTERS-- 254
             ||.:|..|.:.|:||..:..|||.::|...|:|    |.||..|..........::.|..|.
 Worm   176 AGETIRALAIMENHSTKPIINLRFELIQQSHYHS----RPQKSLCSLNDCHSDCPIESKYRRDGE 236

  Fly   255 -------------------FAHELLLPDGAQPTDEQMSGVITIVYELRVEAVLRGF-FKN----- 294
                               ...|:.||:|..||.|  |.:|::.|       |.|| .:|
 Worm   237 TVLRGANYSCDVAPGEVKYINVEIDLPNGLPPTFE--SPMISMGY-------LLGFTLRNGSLTG 292

  Fly   295 --LILNLPFKVYSQ----------DPSNRQSSLRPPPPP 321
              |..|....|.|:          :|:.:...|...|||
 Worm   293 NRLACNARIVVGSEETIDEMVDECEPTKKSQCLTASPPP 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Leash	NP_650037.2	Arrestin_N	6..152	CDD:304627	35/149 (23%)
		Arrestin_C	178..305	CDD:280848	41/159 (26%)
arrd-2	NP_496008.1	Arrestin_N	3..135	CDD:389964	34/147 (23%)
		Arrestin_C	159..305	CDD:367164	42/164 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3780
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D311636at33208
OrthoFinder	1	1.000	-	-		FOG0000089
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11188
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920