Protein Alignment Leash and Txnip

DIOPT Version :9

• Sequence 1: NP_650037.2
• Gene: Leash / 41320
• FlyBaseID: FBgn0037856
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_001008767.1
• Gene: Txnip / 117514
• RGDID: 620886
• Length: 394
• Species: Rattus norvegicus
• Alignment Length: 378
• Identity: 83/378 - (21%)
• Similarity: 154/378 - (40%)
• Gaps: 57/378 - (15%)

  Fly     8 ITLDSADRVYFAGDIIRGEIWMNVNKRTKIRAIKVQVTGKGKCKWMEILRKNSNNNEYSRSLFYT 72
            :..:..::||.:|:.:.|.:.:.|.:.|:::|:::...|..|..||:..::.....:|.|
  Rat    12 VVFNDPEKVYGSGEKVAGRVTVEVCEVTRVKAVRILACGVAKVLWMQGSQQCKQTLDYLR----- 71

  Fly    73 SKEVYEHSETPLPDFEPRG----LELSAG---EHTFIFEVALGRQLPSSFKGSYGAIKYKMRVLI 130
                ||  :|.|.:.:|.|    :.:..|   |:.|.||:..| .|.:||||.||.:.|.::..:
  Rat    72 ----YE--DTLLLEDQPTGENEMVIMRPGNKYEYKFGFELPQG-PLGTSFKGKYGCVDYWVKAFL 129

  Fly   131 QRPWTFDERHTIPFTVVKNMPLQPMQRSIPSSLEKQVTKTISLFGTRPITLLALLPEDFAVRGEP 195
            .||....:.....|.|:..:.:.......|.|.:|:...:........:::.|.:.......|:.
  Rat   130 DRPSQPTQEAKKNFEVMDLVDVNTPDLMAPVSAKKEKKVSCMFIPDGRVSVSARIDRKGFCEGDD 194

  Fly   196 LRICATVINNSTTAVEKLRFTVLQYVTYYSHVPLRV--QKVECIAVATKETGSVQKKTERSFAHE 258
            :.|.|...|..:..|......|.:: ||.::...:|  ||:..:......:|:......:|...:
  Rat   195 ISIHADFENTCSRIVVPKAAIVARH-TYLANGQTKVLTQKLSSVRGNHIISGTCASWRGKSLRVQ 258

  Fly   259 LLLPD--GAQPTDEQMSGVITIVYELRVEAVLRGFFKNLILNLPFKVYSQDP-SNRQSS------ 314
            .:.|.  |.        .::.:.|.|.:...:.| .|.:||:||..:.|:.. |:|.||
  Rat   259 KIRPSILGC--------NILRVEYSLLIYVSVPG-SKKVILDLPLVIGSRSGLSSRTSSMASRTS 314

  Fly   315 -------LRPPPPPRPNDGPPG-----PELGSGNLFEPALPVYPSLDSSIGSP 355
                   |..|..|   :.||.     ||  ...|..|..|:...:|.|..||
  Rat   315 SEMSWIDLNIPDTP---EAPPCYMDVIPE--DHRLESPTTPLLDDVDDSQDSP 362

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Leash	NP_650037.2	Arrestin_N	6..152	CDD:304627	37/150 (25%)
		Arrestin_C	178..305	CDD:280848	24/130 (18%)
Txnip	NP_001008767.1	Arrestin_N	10..152	CDD:304627	37/151 (25%)
		Arrestin_C	174..298	CDD:280848	24/133 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3780
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D311636at33208
OrthoFinder	1	1.000	-	-		FOG0000089
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820