Protein Alignment Leash and arrdc4

DIOPT Version :10

• Sequence 1: NP_650037.2
• Gene: Leash / 41320
• FlyBaseID: FBgn0037856
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_001107732.1
• Gene: arrdc4 / 100135736
• XenbaseID: XB-GENE-492296
• Length: 403
• Species: Xenopus tropicalis
• Alignment Length: 405
• Identity: 88/405 - (21%)
• Similarity: 140/405 - (34%)
• Gaps: 126/405 - (31%)

  Fly    17 YFAGDIIRGEIWMNVNKRTKIRAIKVQVTGKG-KCK--------WMEILRKNSNNNEYSRSLFYT 72
            |.||:.:.|.:.:.|.:..::.::.::|.|.. .||        |          ..:.::..|.
 Frog    19 YCAGEPVTGYVLLEVLREIRVLSLLLRVCGGAMTCKQGKQLEDAW----------EAFPQATHYL 73

  Fly    73 SKEVYEHSETPLPDFEPRGLELSAGEHTFIFEVALGRQ-LPSSFKGSYGAIKYKMRVLIQRP--- 133
            ::| |.....|..|.|.  |...||.|...|...|... |.:||.|.||.:.|:...:::||
 Frog    74 NEE-YSLLTEPAGDCEI--LLFPAGNHKIPFRFQLPESPLVTSFSGKYGKVYYQTTAVLKRPSVP 135

  Fly   134 --WTFDERHTI-PFTVVKNMPLQPMQRSIPSSLEKQVTKTISLFGTRPITLLALLPEDFAVRGEP 195
              .|..|...: |..|.......|::||      |:|......|.:.||::.|.:.......||.
 Frog   136 PHTTHRELRVLSPINVNSPSLYTPVERS------KEVMVGCWFFMSGPISVNAKIGRKGYCNGEA 194

  Fly   196 LRICATVINNSTTAV---------------EKLRFTVLQYVTYY--SHV---------------- 227
            :.|.|.:.|.|:..:               .|.| ||.|.:...  :|:
 Frog   195 IHIYADIENGSSRLIVPKAAIYQTQSFLLDGKTR-TVRQMLASVRGNHIASGSADSWNGKALKIP 258

  Fly   228 PLRVQKVEC--------IAVATKETGSVQKKTERSFAHELLLPDGAQPTDEQMSGVITIVYELRV 284
            |:....:||        :||:....|:.:.|.      ||.|..|..|.:|         :..|.
 Frog   259 PVTPSILECNIIRVEYSLAVSINIPGAKKLKV------ELPLVIGTIPLNE---------FNCRN 308

  Fly   285 EAVLRGFFKN---LILNLPFK----------VYSQDPSNRQSSLR-----------PP------- 318
            .:|...|..:   |.|.||.:          |..:|.|...||:.           ||
 Frog   309 ASVASQFSMDMSWLALALPEQPEAPPNYADIVSEEDLSRDISSMEDIGDVLEGLHCPPFAVIQEF 373

  Fly   319 ---PPPRPNDGPPGP 330
               |||..::..|.|
 Frog   374 RFQPPPLYSEVDPHP 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Leash	NP_650037.2	Arrestin_N	6..152	CDD:451447	35/150 (23%)
		Arrestin_C	191..308	CDD:214976	33/170 (19%)
arrdc4	NP_001107732.1	Arrestin_N	10..152	CDD:451447	34/145 (23%)
		Arrestin_C	175..301	CDD:214976	26/132 (20%)