DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Leash and arrdc4

DIOPT Version :9

Sequence 1:	NP_650037.2	Gene:	Leash / 41320	FlyBaseID:	FBgn0037856	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_001107732.1	Gene:	arrdc4 / 100135736	XenbaseID:	XB-GENE-492296	Length:	403	Species:	Xenopus tropicalis

Alignment Length:	405	Identity:	88/405 - (21%)
Similarity:	140/405 - (34%)	Gaps:	126/405 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 YFAGDIIRGEIWMNVNKRTKIRAIKVQVTGKG-KCK--------WMEILRKNSNNNEYSRSLFYT 72
            |.||:.:.|.:.:.|.:..::.::.::|.|.. .||        |          ..:.::..|.
Frog    19 YCAGEPVTGYVLLEVLREIRVLSLLLRVCGGAMTCKQGKQLEDAW----------EAFPQATHYL 73

  Fly    73 SKEVYEHSETPLPDFEPRGLELSAGEHTFIFEVALGRQ-LPSSFKGSYGAIKYKMRVLIQRP--- 133
            ::| |.....|..|.|.  |...||.|...|...|... |.:||.|.||.:.|:...:::||
Frog    74 NEE-YSLLTEPAGDCEI--LLFPAGNHKIPFRFQLPESPLVTSFSGKYGKVYYQTTAVLKRPSVP 135

  Fly   134 --WTFDERHTI-PFTVVKNMPLQPMQRSIPSSLEKQVTKTISLFGTRPITLLALLPEDFAVRGEP 195
              .|..|...: |..|.......|::||      |:|......|.:.||::.|.:.......||.
Frog   136 PHTTHRELRVLSPINVNSPSLYTPVERS------KEVMVGCWFFMSGPISVNAKIGRKGYCNGEA 194

  Fly   196 LRICATVINNSTTAV---------------EKLRFTVLQYVTYY--SHV---------------- 227
            :.|.|.:.|.|:..:               .|.| ||.|.:...  :|:
Frog   195 IHIYADIENGSSRLIVPKAAIYQTQSFLLDGKTR-TVRQMLASVRGNHIASGSADSWNGKALKIP 258

  Fly   228 PLRVQKVEC--------IAVATKETGSVQKKTERSFAHELLLPDGAQPTDEQMSGVITIVYELRV 284
            |:....:||        :||:....|:.:.|.      ||.|..|..|.:|         :..|.
Frog   259 PVTPSILECNIIRVEYSLAVSINIPGAKKLKV------ELPLVIGTIPLNE---------FNCRN 308

  Fly   285 EAVLRGFFKN---LILNLPFK----------VYSQDPSNRQSSLR-----------PP------- 318
            .:|...|..:   |.|.||.:          |..:|.|...||:.           ||
Frog   309 ASVASQFSMDMSWLALALPEQPEAPPNYADIVSEEDLSRDISSMEDIGDVLEGLHCPPFAVIQEF 373

  Fly   319 ---PPPRPNDGPPGP 330
               |||..::..|.|
Frog   374 RFQPPPLYSEVDPHP 388

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Leash	NP_650037.2	Arrestin_N	6..152	CDD:304627	35/150 (23%)
Leash	NP_650037.2	Arrestin_C	178..305	CDD:280848	36/180 (20%)
arrdc4	NP_001107732.1	Arrestin_N	7..152	CDD:304627	34/145 (23%)
arrdc4	NP_001107732.1	Arrestin_C	175..301	CDD:214976	26/132 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D311636at33208
OrthoFinder	1	1.000	-	-		FOG0000089
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920