Protein Alignment CG6621 and Ttc14

DIOPT Version :10

• Sequence 1: NP_650036.2
• Gene: CG6621 / 41319
• FlyBaseID: FBgn0037855
• Length: 872
• Species: Drosophila melanogaster
• Sequence 2: XP_063137841.1
• Gene: Ttc14 / 310314
• RGDID: 1310045
• Length: 802
• Species: Rattus norvegicus
• Alignment Length: 830
• Identity: 197/830 - (23%)
• Similarity: 334/830 - (40%)
• Gaps: 217/830 - (26%)

  Fly     1 MNFDYIGQALGYHGQPLQKIWDDER------------------------------------GVDD 29
            |:.|.:.|:||.||..|..:...|:                                    |...
  Rat     1 MDRDLLRQSLGCHGPALLSLLRSEQQDNPHFRSLLGTTAEPARGAAPPPGAGRENGLQTSSGTQW 65

  Fly    30 LRLMGLTQVNYGVYQERQKYFTFQERAKRLKMHQFLARKATDLY------DRTLVANVMEDSLLA 88
            ::.:.:...:....::.|.:...::|...:::.:|:::||..|:      |.::.:.|.:|:
  Rat    66 VKALAIEHPHLTDSRDSQGFPAKEKRVDNIEIQKFISKKADLLFALSWKPDASVPSEVHDDN--- 127

  Fly    89 QGNTYMTQMAPFEFFLNV--KDKRKGWAHRLSALKQGDIIYTQVTR------------LASG--- 136
              :.:...|.|.|.|:.:  .|:|:.:   ...:::|||:..:::.            |.||
  Rat   128 --DNHYAVMPPLEQFMEIPSMDRRELF---FRDIERGDIVIGRISSIREFGFFMVLICLGSGIMR 187

  Fly   137 --NRLIVKPLCTAEPKHAYLADIPIKAVILQDFWGPLPLDKQGNPRSFVQ-NDILRCEINNISAD 198
              :.|.:..||.       |.|:|..:             ..|:|.|:.| .||:|..|.:|...
  Rat   188 DISHLEITALCP-------LRDVPSHS-------------NHGDPLSYYQTGDIIRAGIKDIDRY 232

  Fly   199 TERLSLNMIGMFNKVP----DLKFGLCDFKELPKYYSKIHNLDHPSASHYEDELNKALEFENPN- 258
            .|:|::::..  :.:|    .:|.|:...:|||.||.:...|:..|...||:.:..:|.|.||.
  Rat   233 HEKLAVSLYS--SSLPPHLSGIKLGVITSEELPLYYRRSVELNSNSLESYENIMQSSLGFVNPGV 295

  Fly   259 YDLLFQMNGLQPNENLSLMSYLRA-GFPEEENAAELRQKQASQWAFRSVADGIEHFKNGQQVEAF 322
            .:.|.:..|:..:...|||..|:: .|.|::.|:.||:||::.||.:.|..|:::||.|:.|:|.
  Rat   296 VEFLLEKLGIDESHPPSLMRGLQSKNFSEDDFASALRKKQSASWALKCVKIGVDYFKVGRHVDAM 360

  Fly   323 QCLNKALNIDPRNVEALVARGALYANRGSFLKGLQDFEKALHLNKYHVNARKYMGETLVALGRSY 387
            ...||||.||.:|||||||||||||.:||..|.::|||.||.....|.|||||:.:|||..|...
  Rat   361 NEYNKALEIDKQNVEALVARGALYATKGSLNKAIEDFELALENCPTHRNARKYLCQTLVERGGQL 425

  Fly   388 EEENRIAEAVKAYSDCLNLLPLHEEARQSLDALHRSGDGKRRISTEPSNMTGGQSSDESSSSSAS 452
            |||.:...|...|...|.|....::|..:|..||       :...:...:...|:..|....:
  Rat   426 EEEEKFLNAESYYKKALALDETFKDAEDALQKLH-------KYMQKSLELREKQAEKEEKQKT-- 481

  Fly   453 DSECEDSAGKPKSNISQPFYAQHKLKQSGDEKLAVIDAHKANEFRLDDDETVSSVRKLLREASKH 517
             .:.|.||.|.:..:.:....:.|.::|.....:|..|          ||::||...  ..:|.|
  Rat   482 -KKIETSAEKLRKLLKEEKRLKKKRRKSSSSSSSVSSA----------DESISSSSS--SSSSSH 533

  Fly   518 KKAKKKGKKKKDKKERRRSRTKSETEDPIELLKKIDFQEALRQDNKLMNSTRSDEERKAKIKSYL 582
            |: .||.|:.:.:..|...|..|:|                       :|..:|:.||
  Rat   534 KR-HKKSKRNRSESSRSSKRHWSKT-----------------------SSGYTDQSRK------- 567

  Fly   583 KEGGKESPPPPPPMKKTAVSSRKSSFDNVGPSTSRHAASVVGFGGAQPPPAPKFLGQKKHPEPAP 647
                                      |:..|..:..:||              ||.||:..|
  Rat   568 --------------------------DDCYPVPTNTSAS--------------FLNQKQEVE--- 589

  Fly   648 KL----------SFQIKKRPLQMDKLGMLRLAAPAEPLKGGRS----SSSRSRSRSRSRSRSRSR 698
            ||          :.|:|::     :.|:|..:.......||||    |.......|::....:|.
  Rat   590 KLLEKQDRLQCPNAQVKEK-----EKGLLTSSVEVPDDLGGRSDLYNSYKTQAGSSKTEKPYKSE 649

  Fly   699 NRRLGRSTRSSLRSRRSGSRSRSISRSRSRR----RRTYSRSRSPSPRSY 744
            .....|...|...||.|..:.::.|..|..:    |:.:||...||...|
  Rat   650 KHFSSRRNSSDCFSRNSEDKMKASSYRRFEKDTEGRKDHSRRWEPSSGKY 699

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6621	NP_650036.2	Spy	226..>425	CDD:443119	82/200 (41%)
		TPR repeat	335..365	CDD:276809	21/29 (72%)
		TPR repeat	370..404	CDD:276809	14/33 (42%)
Ttc14	XP_063137841.1	None