Protein Alignment CG6621 and LOC1279042

DIOPT Version :10

• Sequence 1: NP_650036.2
• Gene: CG6621 / 41319
• FlyBaseID: FBgn0037855
• Length: 872
• Species: Drosophila melanogaster
• Sequence 2: XP_061513140.1
• Gene: LOC1279042 / 1279042
• VectorBaseID: AGAMI1_011092
• Length: 1300
• Species: Anopheles gambiae
• Alignment Length: 1167
• Identity: 359/1167 - (30%)
• Similarity: 495/1167 - (42%)
• Gaps: 339/1167 - (29%)

  Fly     4 DYIGQALGYHGQPLQKIWDDERGVDDLRLMGL-TQVNYGVYQERQKYFTFQERAKRLKMHQFLAR 67
            :.|.|||.|||:||||||:.||..::|..:|: ..::|.||..|||:||.|:||||||:.||:||
Mosquito    10 ELIQQALVYHGRPLQKIWETERRQNELLALGIDANLDYSVYMARQKHFTLQDRAKRLKLQQFMAR 74

  Fly    68 KATDLYDRTLVANVMEDSL-LAQGNTYMTQMAPFEFFLNVKDKRKGWAHRLSALKQGDIIYTQVT 131
            ||..||......:..|..: ..|.|.:  .:.|.:.||:. :.....||.|..:..||::|..||
Mosquito    75 KANVLYGADTQHSAREPEIDYRQSNHF--AIPPMDTFLDT-EADGSTAHLLETVLPGDVVYGTVT 136

  Fly   132 RLASGNRLIVKPLCTAEPKHAYLADIPIKAVILQDFWGPLPLDKQ-GNPRSFVQNDILRCEINNI 195
            ...:...:..:||.......:::.:..||..:..|  ..|..||. |.|:::..||::.||:.::
Mosquito   137 MFKNFGGIAFRPLLIVGNVTSFVRNKLIKGTVASD--QVLTPDKDPGAPKNYFVNDMICCEVIDV 199

  Fly   196 SADTERLSLNMIGMF-NKVPD-LKFGLCDFKELPKYY-SKIHNLDHPSASHYEDELNKALEFENP 257
            :.|..||..:|.... ::.|| :.:||...:::|:.| :.:...|    .:|:..|:.:..|.:|
Mosquito   200 APDARRLICSMKRTSKSRAPDTVVYGLLSKEDIPEVYKTTLKRKD----QNYQYFLDSSPSFNDP 260

  Fly   258 NY-DLLFQMNGLQPNENLSLMSYLRAGFPEEENAAELRQKQASQWAFRSVADGIEHFKNGQQVEA 321
            |: :.|:|..||..||..:.||.|:..:|.:|.|||||..|.|:|||||||.||||||.|:..||
Mosquito   261 NHIEQLYQEVGLDFNEVYTNMSSLKGRYPSQEYAAELRNSQNSKWAFRSVAQGIEHFKEGRHSEA 325

  Fly   322 FQCLNKALNIDPRNVEALVARGALYANRGSFLKGLQDFEKALHLNKYHVNARKYMGETLVALGRS 386
            ||||||||::||||||.||||||||||.|||.|.::|||.||.||..|.||||||||||||||||
Mosquito   326 FQCLNKALSMDPRNVEGLVARGALYANSGSFKKAVEDFETALKLNPSHANARKYMGETLVALGRS 390

  Fly   387 YEEENRIAEAVKAYSDCLNLLPLHEEARQSLDAL------------------------------- 420
            ||||||..||.|||.||||::|.||||:.|||.|
Mosquito   391 YEEENRFEEAKKAYQDCLNIIPHHEEAQNSLDFLKSKPFTGKQIVEPTELELPSLNIIKPSSSDR 455

  Fly   421 --------------------------HRSGDGKRR-----------------------ISTEPSN 436
                                      |..|...|:                       .||:.|:
Mosquito   456 NKQEPDTSGVGGSGVFGAGSSGSKRDHLDGSSSRKDRKKESKKERKKRHKKHHSSSSDSSTDSSD 520

  Fly   437 MTGGQSSDESSSSSASDSECEDSAG-------------KPKS----------------------- 465
             :...|||.|||||.:.:...||:|             ||||
Mosquito   521 -SSDSSSDSSSSSSTASTTSSDSSGSRNKKRKRSKNDKKPKSISPMGKRLSSAGGGGRGGGPSAG 584

  Fly   466 -NISQPFYAQ----------HKLKQSGDEKLAVIDAHKANEFRLDDDETVSSVRKLLREASKHKK 519
             .:..|...|          |......|.:..|   .|..|...|::.....||:.:.||||::|
Mosquito   585 EMVGYPIGGQGGSVFGHSSSHGQSAMDDYEQKV---RKFLEMPRDEENYEEKVRRFVAEASKYQK 646

  Fly   520 AKK------KGKKKKDKKERRRSRTKSETEDPIELLKKID---------FQEALRQDNKLMNSTR 569
            .:|      |.|||||:|:.::...|....|..:..||.|         .::.||:..|:..:..
Mosquito   647 ERKQMEDKSKKKKKKDEKKAKKESKKKRKSDEKKKSKKKDKGGDDDGLGNKDKLREALKIFENFP 711

  Fly   570 SDEERKAKIK---------SYLKEGG--------------------------------------- 586
            ..:|..:|:.         |.|..||
Mosquito   712 VLDELGSKLSVGGSVAEALSALLGGGTGSGSGGGAGTSRAKPTDALDLERAGIAPGGDENAKEGK 776

  Fly   587 ------KESPP--PPPPMKKTAVSS----RKSSFDN--------VGPS---------------TS 616
                  |:..|  .|.|:..|.:::    ::..|.|        .|||               :|
Mosquito   777 WRMMFNKDKRPAKEPAPIAATTLTAGLGLKQHPFSNESDEESVGAGPSFTIGGKMPQNDRGTTSS 841

  Fly   617 RHAASVVG------FGGAQPPPAPKFLGQKKHPEPAPKLSFQIKKRPLQMDKLGMLRLAA----- 670
            |...|..|      :|..:..|:.|...........|    .:|..|:.:||.|..|||:
Mosquito   842 RFGGSGGGASGGGRYGDDRGGPSEKGKAASSTAAQMP----AVKSGPVVLDKFGNFRLASADAPS 902

  Fly   671 ------PAEPLKGGRSSSSRSRSRSR----SRSRSRSRNRRLGRSTRSSLRSRRSGSRSRSISRS 725
                  |.||........|||:||:|    ||||||||:.| .||...|.|.|.|.|||||.|||
Mosquito   903 AAGGSKPPEPSAAPPMRRSRSKSRTRNYGSSRSRSRSRSDR-RRSRSGSFRRRFSRSRSRSFSRS 966

  Fly   726 RS-RRRRTYSRSRSPSPRSYGNRFV---------------------IGRYRNRRTRRSRSFHRRR 768
            || ...|:.|||||...|.:..||.                     :|.:...|...||..:||.
Mosquito   967 RSGSYSRSRSRSRSFERRRFDRRFYRGGRGGGGGGGGGGGGYGGDRMGPFGGNRFNNSRGHYRRG 1031

  Fly   769 SPSPILKR----------------RSPSPFVPRRTPSPASRYRRSRSRSRSRSRSRSP------- 810
            ........                |...||.||.    ..|::||.|||.|:|..|.|
Mosquito  1032 GFRDFRDNRFVGGPRGGGGGMGGGRDRPPFRPRY----RGRFQRSYSRSMSKSPDRRPISPGDDR 1092

  Fly   811 -RRFQSRYMPRDRGSVNRSRYSWHNPHKRSVSRTVEPNGKDERAATPPKKGVADDRSGREER 871
             |.:|.|...||||:..          :|..||        ||::.|.::..||.|..:.:|
Mosquito  1093 SRHYQRRGDSRDRGTAG----------QRGDSR--------ERSSPPTRRSRADSRDNQRDR 1136

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6621	NP_650036.2	Spy	226..>425	CDD:443119	119/257 (46%)
		TPR repeat	335..365	CDD:276809	22/29 (76%)
		TPR repeat	370..404	CDD:276809	28/33 (85%)
LOC1279042	XP_061513140.1	None