DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Adk3 and Ak3

DIOPT Version :9

Sequence 1:	NP_001287279.1	Gene:	Adk3 / 41318	FlyBaseID:	FBgn0042094	Length:	216	Species:	Drosophila melanogaster
Sequence 2:	XP_006527285.1	Gene:	Ak3 / 56248	MGIID:	1860835	Length:	263	Species:	Mus musculus

Alignment Length:	184	Identity:	98/184 - (53%)
Similarity:	130/184 - (70%)	Gaps:	0/184 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 KIFRAVIIGAPGSGKGTISELICKNHGCVHISTGDILRQNIIKNTELGKKAKQYIAEGKLVPDAI 68
            ::.||||:|||||||||:|..|.|:....|:|:||:||||:::.||:|..||.:|.:|||:||.:
Mouse     6 RLLRAVIMGAPGSGKGTVSSRITKHFELKHLSSGDLLRQNMLQGTEIGVLAKTFIDQGKLIPDDV 70

  Fly    69 VTKTMLARITEVGNRSYILDGFPRNIAQAEALAAREQIDAVITLDVPHSVIIDRVKNRWIHAPSG 133
            :|:..|..:..:...|::||||||.:.|||||....|||.||.|:||..||..|:..||||..||
Mouse    71 MTRLALHELKTLTQCSWLLDGFPRTLPQAEALDKVYQIDTVINLNVPFEVIKQRLTARWIHPASG 135

  Fly   134 RVYNIGFKNPKVPGKDDVTGEPLMQREDDKPHVVAKRLELYDEVMSPVIAWYEK 187
            |||||.|..||..|.||:|||||:|||||||..|.|||:.|:....||:.:|:|
Mouse   136 RVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEAQTEPVLQYYQK 189

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adk3	NP_001287279.1	adk	7..211	CDD:273569	98/181 (54%)
Adk3	NP_001287279.1	ADK	7..201	CDD:238713	98/181 (54%)
Ak3	XP_006527285.1	ADK	12..189	CDD:366082	94/176 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837176
Domainoid	1	1.000	198	1.000	Domainoid score	I3081
eggNOG	1	0.900	-	-		E1_COG0563
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H21744
Inparanoid	1	1.050	226	1.000	Inparanoid score	I3474
Isobase	1	0.950	-	0	Normalized mean entropy	S722
OMA	1	1.010	-	-		QHG53706
OrthoDB	1	1.010	-	-		D1004067at2759
OrthoFinder	1	1.000	-	-		FOG0003066
OrthoInspector	1	1.000	-	-		otm42938
orthoMCL	1	0.900	-	-		OOG6_103907
Panther	1	1.100	-	-	LDO	PTHR23359
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2169
SonicParanoid	1	1.000	-	-		X2043
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	17	16.750