DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Adk3 and ak7b

DIOPT Version :9

Sequence 1:	NP_001287279.1	Gene:	Adk3 / 41318	FlyBaseID:	FBgn0042094	Length:	216	Species:	Drosophila melanogaster
Sequence 2:	NP_001103168.2	Gene:	ak7b / 504040	ZFINID:	ZDB-GENE-050309-170	Length:	699	Species:	Danio rerio

Alignment Length:	219	Identity:	54/219 - (24%)
Similarity:	87/219 - (39%)	Gaps:	71/219 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 RAVIIGAPGSGKGTISELICKNHGCVHIST------------------------------GDILR 41
            |..|:|.|..||.||:|.|||::...||..                              .|.||
Zfish   363 RMCIVGPPAVGKSTIAEKICKHYNLHHIKLKEAIAEALENLELCVRTEDEENDQDDDQEFWDTLR 427

  Fly    42 QNIIKNTELGKKAKQYIAEGKLVPDAIVTKTMLARITEVGNRSYILDGFPRNIAQAEAL----AA 102
            :|:.:|.  |:...||:.  :::.|.:.||..:       |:.::|||||:...||:.|    ..
Zfish   428 ENMNENG--GRLDDQYVI--RIMKDKLRTKPCM-------NQGFVLDGFPKTCEQAKELFTGDGE 481

  Fly   103 REQIDAV-ITLDVPHSVII-----DRVKNRWIHAPSGRVYNIGFKNPKVPGKDDVTGEPLMQR-- 159
            .|.:::. .|..:|..|..     |.:|||.::.|...|....:    :|       |..:||
Zfish   482 PEDLESKHATKIIPEFVFSVNATDDFLKNRVLNLPETVVEGTSY----MP-------EQFLQRLA 535

  Fly   160 -------EDDKPHVVAKRLELYDE 176
                   ||:.|....:.||::.|
Zfish   536 RFRDRNVEDEMPLNYFEDLEIHPE 559

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adk3	NP_001287279.1	adk	7..211	CDD:273569	54/219 (25%)
Adk3	NP_001287279.1	ADK	7..201	CDD:238713	54/219 (25%)
ak7b	NP_001103168.2	WcaG	<129..>286	CDD:223528
		NADB_Rossmann	<212..286	CDD:304358
		Adk	363..583	CDD:223637	54/219 (25%)
		ADK	363..556	CDD:238713	52/214 (24%)
		Dpy-30	656..697	CDD:253069
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0563
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900