DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Adk3 and ak3

DIOPT Version :9

Sequence 1:	NP_001287279.1	Gene:	Adk3 / 41318	FlyBaseID:	FBgn0042094	Length:	216	Species:	Drosophila melanogaster
Sequence 2:	NP_998295.2	Gene:	ak3 / 406404	ZFINID:	ZDB-GENE-040426-2142	Length:	225	Species:	Danio rerio

Alignment Length:	210	Identity:	106/210 - (50%)
Similarity:	149/210 - (70%)	Gaps:	0/210 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 IFRAVIIGAPGSGKGTISELICKNHGCVHISTGDILRQNIIKNTELGKKAKQYIAEGKLVPDAIV 69
            :|||||:|||||||||:|..|.::.|..|:|:||:||.||...|:||...|..|.:|:||||.::
Zfish     6 VFRAVIMGAPGSGKGTVSSRIAQSFGLKHLSSGDMLRANIEAKTDLGLLMKSCIDQGQLVPDDVI 70

  Fly    70 TKTMLARITEVGNRSYILDGFPRNIAQAEALAAREQIDAVITLDVPHSVIIDRVKNRWIHAPSGR 134
            ::.:|:.:..:...|::||||||.:||||||.....:|:||.||||...|.:|:.:||:|.||||
Zfish    71 SRLILSSLRGLEKTSWLLDGFPRTVAQAEALDCVYDVDSVINLDVPFQTIRERLTSRWVHLPSGR 135

  Fly   135 VYNIGFKNPKVPGKDDVTGEPLMQREDDKPHVVAKRLELYDEVMSPVIAWYEKKGLVATFKGKQT 199
            ||||.|..||.||.||||||||:||:||.|..|::||:.|:....||:.:|..||::.||.|.:|
Zfish   136 VYNIDFNPPKKPGLDDVTGEPLVQRDDDSPETVSRRLKDYERQTQPVLEYYRSKGVLETFSGTET 200

  Fly   200 KEIWPMMELFLNDRI 214
            .:|||.:..||:.:|
Zfish   201 NKIWPHVHTFLSRKI 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adk3	NP_001287279.1	adk	7..211	CDD:273569	103/203 (51%)
Adk3	NP_001287279.1	ADK	7..201	CDD:238713	99/193 (51%)
ak3	NP_998295.2	ADK	8..200	CDD:238713	98/191 (51%)
ak3	NP_998295.2	adk	8..198	CDD:234711	97/189 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580756
Domainoid	1	1.000	195	1.000	Domainoid score	I3102
eggNOG	1	0.900	-	-		E1_COG0563
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H21744
Inparanoid	1	1.050	227	1.000	Inparanoid score	I3455
OMA	1	1.010	-	-		QHG53706
OrthoDB	1	1.010	-	-		D1004067at2759
OrthoFinder	1	1.000	-	-		FOG0003066
OrthoInspector	1	1.000	-	-		otm24331
orthoMCL	1	0.900	-	-		OOG6_103907
Panther	1	1.100	-	-	LDO	PTHR23359
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2169
SonicParanoid	1	1.000	-	-		X2043
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800