DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Adk3 and Ak4

DIOPT Version :9

Sequence 1:	NP_001287279.1	Gene:	Adk3 / 41318	FlyBaseID:	FBgn0042094	Length:	216	Species:	Drosophila melanogaster
Sequence 2:	NP_058831.1	Gene:	Ak4 / 29223	RGDID:	2078	Length:	223	Species:	Rattus norvegicus

Alignment Length:	214	Identity:	100/214 - (46%)
Similarity:	145/214 - (67%)	Gaps:	0/214 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFTKIFRAVIIGAPGSGKGTISELICKNHGCVHISTGDILRQNIIKNTELGKKAKQYIAEGKLVP 65
            |.:|:.||||:|.|||||||:.|.|.:|.|..|:|:|.:||:|:..|||:|..||||:.:|.|||
  Rat     1 MASKLLRAVILGPPGSGKGTVCERIAQNFGLQHLSSGHLLRENLKTNTEVGDVAKQYLEKGLLVP 65

  Fly    66 DAIVTKTMLARITEVGNRSYILDGFPRNIAQAEALAAREQIDAVITLDVPHSVIIDRVKNRWIHA 130
            |.::|:.|::.:.....:.::||||||.:.|||||.....:|.||:|::|...:.||:..||||.
  Rat    66 DHVITRLMMSELETRSAQHWLLDGFPRTLVQAEALDRICDVDLVISLNIPFETLKDRLSRRWIHP 130

  Fly   131 PSGRVYNIGFKNPKVPGKDDVTGEPLMQREDDKPHVVAKRLELYDEVMSPVIAWYEKKGLVATFK 195
            .||||||:.|..|:|.|.||:|||||:|:|||||..:|.||..|.:...|||..|:.:|::..|.
  Rat   131 SSGRVYNLDFNPPQVLGVDDITGEPLVQQEDDKPEALAARLRRYKDAAKPVIELYKSRGVLHQFS 195

  Fly   196 GKQTKEIWPMMELFLNDRI 214
            |.:|..|||.:....:::|
  Rat   196 GTETNRIWPYVYTLFSNKI 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adk3	NP_001287279.1	adk	7..211	CDD:273569	97/203 (48%)
Adk3	NP_001287279.1	ADK	7..201	CDD:238713	94/193 (49%)
Ak4	NP_058831.1	adk	7..211	CDD:273569	97/203 (48%)
		NMP. /evidence=ECO:0000255\|HAMAP-Rule:MF_03170	35..64		14/28 (50%)
		LID. /evidence=ECO:0000255\|HAMAP-Rule:MF_03170	125..162		23/36 (64%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	190	1.000	Domainoid score	I3172
eggNOG	1	0.900	-	-		E1_COG0563
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	216	1.000	Inparanoid score	I3516
OMA	1	1.010	-	-		QHG53706
OrthoDB	1	1.010	-	-		D1004067at2759
OrthoFinder	1	1.000	-	-		FOG0003066
OrthoInspector	1	1.000	-	-		otm45007
orthoMCL	1	0.900	-	-		OOG6_103907
Panther	1	1.100	-	-	O	PTHR23359
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2043
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.880