DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Adk3 and F13E6.2

DIOPT Version :9

Sequence 1:	NP_001287279.1	Gene:	Adk3 / 41318	FlyBaseID:	FBgn0042094	Length:	216	Species:	Drosophila melanogaster
Sequence 2:	NP_509786.2	Gene:	F13E6.2 / 181264	WormBaseID:	WBGene00008746	Length:	729	Species:	Caenorhabditis elegans

Alignment Length:	217	Identity:	48/217 - (22%)
Similarity:	92/217 - (42%)	Gaps:	40/217 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 VIIGAPGSGKGTISELICKNH-GCVHISTGDILRQNI--IKNTELGKKAKQYIAEGKLVPDAIVT 70
            :::|||||.|..||..|.:.: |...:|.|||||:.|  .||.|:..|..:.:..|..:|..:..
Worm   517 LVLGAPGSQKNDISRRIAQKYDGFTMLSMGDILRKKINNEKNDEMWDKVSKKMNNGDPIPTKMCR 581

  Fly    71 KTMLARITEVG--NRSYILDGFPRNIAQAEALA-AREQIDAVITLDVPHSVIIDRVKNRWIHAPS 132
            ..:...:...|  |..|:::|:|::..|...|. :.::.|..|.:|......::.:..|
Worm   582 TVLYEELHSRGTSNWGYVIEGYPKSPDQLVDLEHSLQRTDLAILIDCTEQFCLEVINKR------ 640

  Fly   133 GRVYNIGFKNPKVPGKDDVTGEPLMQREDDKPHVVAKRLELYDEVMSPVIAWYEKKGLVATFKGK 197
                          .:::       :|.||....|..|:|.:.:...|::...:.||.:....|.
Worm   641 --------------NREN-------KRSDDDSDAVRSRMEYFKKNTLPMLKTLDDKGKLRVVDGD 684

  Fly   198 QT-----KEIWPMME--LFLND 212
            ..     ||:..:::  |::.|
Worm   685 ADPDTVFKEVVQVIDRTLYVED 706

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adk3	NP_001287279.1	adk	7..211	CDD:273569	47/214 (22%)
Adk3	NP_001287279.1	ADK	7..201	CDD:238713	44/202 (22%)
F13E6.2	NP_509786.2	aden_kin_iso1	168..355	CDD:130427
		ADK	171..337	CDD:238713
		aden_kin_iso1	514..699	CDD:130427	46/208 (22%)
		ADK	515..690	CDD:238713	44/199 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0563
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810