DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Adk3 and let-754

DIOPT Version :9

Sequence 1:	NP_001287279.1	Gene:	Adk3 / 41318	FlyBaseID:	FBgn0042094	Length:	216	Species:	Drosophila melanogaster
Sequence 2:	NP_001370509.1	Gene:	let-754 / 176118	WormBaseID:	WBGene00002879	Length:	251	Species:	Caenorhabditis elegans

Alignment Length:	203	Identity:	76/203 - (37%)
Similarity:	118/203 - (58%)	Gaps:	7/203 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 RAVIIGAPGSGKGTISELICKNHGCVHISTGDILRQNIIKNTELGKKAKQYIAEGKLVPDAIVTK 71
            ||:.||.|||||||.:....:.:...|::|||:||..:...:|.||:.|..:..||||.|.:|.|
Worm    28 RAIFIGPPGSGKGTQAPAFAQKYFSCHLATGDLLRAEVASGSEFGKELKATMDAGKLVSDEVVCK 92

  Fly    72 TMLARITEVGNR-SYILDGFPRNIAQAEAL-----AAREQIDAVITLDVPHSVIIDRVKNRWIHA 130
            .:..::.:...: .:|||||||...|||.|     ..:..:|.|:..::...:::.|:..|..|.
Worm    93 LIEQKLEKPECKYGFILDGFPRTSGQAEKLDEILERRKTPLDTVVEFNIADDLLVRRITGRLFHI 157

  Fly   131 PSGRVYNIGFKNPKVPGKDDVTGEPLMQREDDKPHVVAKRLELYDEVMSPVIAWYEKKGL-VATF 194
            .|||.|::.||.||||.|||:|||||::|.||....:.|||..|.::..|::.:|:|.|: ||..
Worm   158 ASGRSYHLEFKPPKVPMKDDLTGEPLIRRSDDNEETLRKRLVQYHQMTVPLVDYYKKHGVHVAVD 222

  Fly   195 KGKQTKEI 202
            ..|...::
Worm   223 AAKPMTDV 230

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adk3	NP_001287279.1	adk	7..211	CDD:273569	76/203 (37%)
Adk3	NP_001287279.1	ADK	7..201	CDD:238713	76/200 (38%)
let-754	NP_001370509.1	ADK	31..215	CDD:395329	69/183 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0563
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53706
OrthoDB	1	1.010	-	-		D1004067at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.830