DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Adk3 and ak5

DIOPT Version :9

Sequence 1:	NP_001287279.1	Gene:	Adk3 / 41318	FlyBaseID:	FBgn0042094	Length:	216	Species:	Drosophila melanogaster
Sequence 2:	NP_001093554.1	Gene:	ak5 / 100003595	ZFINID:	ZDB-GENE-030131-8256	Length:	563	Species:	Danio rerio

Alignment Length:	200	Identity:	52/200 - (26%)
Similarity:	95/200 - (47%)	Gaps:	36/200 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 VIIGAPGSGKGTISELICKNHGCVHISTGDILRQNIIKNTELGKK---AKQYIAEGKLVPDAIVT 70
            :|||.|||||||....|.:.:|..::|.|::||:.:|.|....:|   ..:.|..|:|.|.....
Zfish   136 LIIGGPGSGKGTQCLKIAERYGFEYVSVGELLRKKMIHNATSNRKWSLIARIITNGELAPQETTI 200

  Fly    71 KTMLARITEVGNRS-YILDGFPRNIAQAEALAAREQI---DAVITLDVPHSVIIDRVKNRWIHAP 131
            ..:..:|.::...| .::|||||::.|  ||:..:|:   |.|:.|...:..:.:|::.|
Zfish   201 TEIKQKIMKIPEASGIVIDGFPRDVGQ--ALSFEDQVCTPDLVVFLACSNQRLKERLEKR----- 258

  Fly   132 SGRVYNIGFKNPKVPGKDDVTGEPLMQREDDKPHVVAKRLELYDEVMSPVIAWYEKKGLVATFKG 196
                             .:..|.|     ||.|..:.:||..:.:...|::.::::|||:.|...
Zfish   259 -----------------AEQQGRP-----DDNPKAIDRRLTNFKQNAIPLVKYFQEKGLIVTLDA 301

  Fly   197 KQTKE 201
            .:.:|
Zfish   302 DRDEE 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adk3	NP_001287279.1	adk	7..211	CDD:273569	51/199 (26%)
Adk3	NP_001287279.1	ADK	7..201	CDD:238713	51/198 (26%)
ak5	NP_001093554.1	aden_kin_iso1	133..317	CDD:130427	51/199 (26%)
		ADK	134..308	CDD:238713	51/199 (26%)
		aden_kin_iso1	375..562	CDD:130427
		ADK	379..552	CDD:238713
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0563
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23359
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.910