Protein Alignment CG14696 and ARRDC4

DIOPT Version :9

• Sequence 1: NP_650035.1
• Gene: CG14696 / 41317
• FlyBaseID: FBgn0037853
• Length: 457
• Species: Drosophila melanogaster
• Sequence 2: NP_899232.2
• Gene: ARRDC4 / 91947
• HGNCID: 28087
• Length: 418
• Species: Homo sapiens
• Alignment Length: 436
• Identity: 100/436 - (22%)
• Similarity: 164/436 - (37%)
• Gaps: 80/436 - (18%)

  Fly     5 VNFVFDSNPLGLYQAGQLISGTAELITERPKTIRSIFITINGYGETRWQESEERVGEDGKTTKSL 69
            :..||:....|.|.:|:.::|...|....|..:|::.:...|.....|..|  .......:|.:|
Human    20 LGLVFEDERKGCYSSGETVAGHVLLEASEPVALRALRLEAQGRATAAWGPS--TCPRASASTAAL 82

  Fly    70 VTHTTTE---VYYSTDQPVYGQAGGSQLELPTGKYVFPFRATIPPNAP--TSFNGAHGQIKHEVT 129
            ...:..|   |..|..:|   .||...:.|..||:.||||..: |:.|  |||.|.:|.|::.|.
Human    83 AVFSEVEYLNVRLSLREP---PAGEGIILLQPGKHEFPFRFQL-PSEPLVTSFTGKYGSIQYCVR 143

  Fly   130 LTIDRAVRYNNTFKQCFTVILPHDLNRRLEYKEPLQRLESKSFWWGSIFGAHKPMIMDVSTSYSA 194
            ..::|....:.:.|:...|:...|:|........|:..|.....|   |....|:.:........
Human   144 AVLERPKVPDQSVKRELQVVSHVDVNTPALLTPVLKTQEKMVGCW---FFTSGPVSLSAKIERKG 205

  Fly   195 YVPGQKIHFHLVLDNQSDVQCMDVKVRLIKNVSYRANSSGAKEQLKVTESRVADKHC-------- 251
            |..|:.|..:..::|.|. :.:..|..:.:..:|.|  ||..:.::...:.|...|.
Human   206 YCNGEAIPIYAEIENCSS-RLIVPKAAIFQTQTYLA--SGKTKTIRHMVANVRGNHIASGSTDTW 267

  Fly   252 -GEVLKHNKAKFDEFLTVPPTTPSTQSEKDPIRVSYTLRFIAKTFKLHGGGDLVMDFPITIGTVP 315
             |:.||           :||.|||. .:...|||.|:|   |....:.|...|:::.|:.|||:|
Human   268 NGKTLK-----------IPPVTPSI-LDCCIIRVDYSL---AVYIHIPGAKKLMLELPLVIGTIP 317

  Fly   316 LLGSADDKGPGAEK-------------SQPSGASHPGSPNFQEDVSDEQFESNTFKPRYPVYPFD 367
            ..|........|.:             .||.     ..||:.:.||:|:|..:       :.|:.
Human   318 YNGFGSRNSSIASQFSMDMSWLTLTLPEQPE-----APPNYADVVSEEEFSRH-------IPPYP 370

  Fly   368 GKPGTNGSNGAANF----------PSLY----PKAEEAHPATPVKF 399
            ..|...|......|          |.||    |...:...:.||.|
Human   371 QPPNCEGEVCCPVFACIQEFRFQPPPLYSEVDPHPSDVEESQPVSF 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14696	NP_650035.1	Arrestin_N	5..155	CDD:278754	40/154 (26%)
		Arrestin_C	182..313	CDD:280848	31/139 (22%)
ARRDC4	NP_899232.2	Arrestin_N	26..169	CDD:278754	38/148 (26%)
		Arrestin_C	191..318	CDD:214976	33/144 (23%)
		PPxY motif 1. /evidence=ECO:0000305	350..353		1/2 (50%)
		PPxY motif 2. /evidence=ECO:0000305	395..398		1/2 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	63	1.000	Domainoid score	I10233
eggNOG	1	0.900	-	-		E1_KOG3780
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D311636at33208
OrthoFinder	1	1.000	-	-		FOG0000089
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X122
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.820